Overview

  • Product name

    Recombinant Human LTC4S protein
  • Protein length

    Full length protein

Description

  • Nature

    Recombinant
  • Source

    Wheat germ
  • Amino Acid Sequence
    • Species

      Human
    • Sequence

      MKDEVALLAAVTLLGVLLQAYFSLQVISARRAFRVSPPLTTGPPEFERVY RAQVNCSEYFPLFLATLWVAGIFFHEGAAALCGLVYLFARLRYFQGYARS AQLRLAPLYASARALWLLVALAALGLLAHFLPAALRAALLGRLRTLLPWA
    • Amino acids

      1 to 150
    • Tags

      GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab158833 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Western blot

  • Form

    Liquid
  • Additional notes

    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • Leukotriene C(4) synthase
    • leukotriene C4 synthase
    • LTC4 synthase
  • Relevance

    LTC4S catalyzes the conjugation of leukotriene A4 with reduced glutathione to form leukotriene C4. LTC4S activity is present in eosinophils, basophils, mast cells, certain phagocytic mononuclear cells, endothelial cells, vascular smooth muscle cells and platelets. Deficiency in this protein causes a fatal neurometabolic developmental disorder. It is associated with muscular hypotonia, psychomotor retardation, failure to thrive, and microcephaly.
  • Cellular localization

    Nucleus outer membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein

Images

  • ab158833 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab158833 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab158833.
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