Description

  • Product name

    Recombinant Human LXN/TCI protein
    See all LXN/TCI proteins and peptides
  • Purity

    > 95 % SDS-PAGE.
    ab87145 was purified using conventional chromatography. Endotoxin Level: < 1.0 EU per 1 µg of protein (determined by LAL method )
  • Expression system

    Escherichia coli
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MEIPPTNYPA SRAALVAQNY INYQQGTPHR VFEVQKVKQA SMEDIPGRGH KYRLKFAVEE IIQKQVKVNC TAEVLYPSTG QETAPEVNFT FEGETGKNPD EEDNTFYQRL KSMKEPLEAQ NIPDNFGNVS PEMTLVLHLA WVACGYIIWQ NSTEDTWYKM VKIQTVKQVQ RNDDFIELDY TILLHNIASQ EIIPWQMQVL WHPQYGTKVK HNSRLPKEVQ LE

Specifications

Our Abpromise guarantee covers the use of ab87145 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Liquid
  • Additional notes

    Protein previously labeled as LXN.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    pH: 7.50
    Constituents: 0.316% Tris HCl, 10% Glycerol, 0.29% Sodium chloride

General Info

  • Alternative names

    • ECI
    • Endogenous carboxypeptidase inhibitor
    • Latexin
    • Latexin protein
    • LXN
    • LXN_HUMAN
    • MUM
    • Protein MUM
    • TCI
    • Tissue carboxypeptidase inhibitor
    see all
  • Function

    Hardly reversible, non-competitive, and potent inhibitor of CPA1, CPA2 and CPA4.
  • Tissue specificity

    Highly expressed in heart, prostate, ovary, kidney, pancreas, and colon, moderate or low in other tissues including brain.
  • Sequence similarities

    Belongs to the protease inhibitor I47 (latexin) family.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt

Images

  • 15% SDS-PAGE showing ab87145 (3ug)

References

This product has been referenced in:

  • Xue ZX  et al. Latexin inhibits the proliferation of CD133+ miapaca-2 pancreatic cancer stem-like cells. World J Surg Oncol 12:404 (2014). Functional Studies . Read more (PubMed: 25551472) »
See 1 Publication for this product

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