Recombinant Human M6PR (cation dependent) protein (ab80157)

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Description

  • Product name

    Recombinant Human M6PR (cation dependent) protein
    See all M6PR (cation dependent) proteins and peptides

  • Expression system

    Escherichia coli

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      MFPFYSCWRTGLLLLLLAVAVRESWQTEEKTCDLVGEKGKESEKELALVK RLKPLFNKSF

    • Amino acids

      1 to 60

Specifications

Our Abpromise guarantee covers the use of ab80157 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

    SDS-PAGE

  • Form

    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Constituent: PBS

  • Reconstitution
    Redissolve the powder with 1ml sterile water will restore to the original concentration 1mg/ml.

General Info

  • Alternative names

    • 46 kDa mannose 6 phosphate receptor
    • 46 kDa mannose 6-phosphate receptor
    • Cation dependent mannose 6 phosphate receptor
    • Cation dependent mannose 6 phosphate receptor precursor
    • Cation-dependent mannose-6-phosphate receptor
    • CD Man 6 P receptor
    • CD Man-6-P receptor
    • CD MPR
    • CD-M6PR
    • CD-MPR
    • FLJ32994
    • M6pr
    • M6PR protein
    • Man6PR
    • Mannose 6 phosphate receptor
    • Mannose 6 phosphate receptor (cation dependent)
    • MPR 46
    • MPR46
    • MPRD
    • MPRD_HUMAN
    • Mr 46,000 Man6PR
    • Small mannose 6 phosphate receptor
    • SMPR
    see all

  • Function

    Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex.

  • Domain

    The extracellular domain is homologous to the repeating units (of approximately 147 AA) of the cation-independent mannose 6-phosphate receptor.

  • Cellular localization

    Lysosome membrane.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human M6PR (cation dependent) protein (ab80157)
    SDS-PAGE - Recombinant Human M6PR (cation dependent) protein (ab80157)
    20% SDS PAGE showing ab80157 at approximately 12 kDa.

References

ab80157 has not yet been referenced specifically in any publications.

Publishing research using ab80157? Please let us know so that we can cite the reference in this datasheet.

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