Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MGSSHHHHHH SSGLVPRGSH MGSMAVQESA AQLSMTLKVQ EYPTLKVPYE TLNKRFRAAQ KNIDRETSHV TMVVAELEKT LSGCPAVDSV VSLLDGVVEK LSVLKRKAVE SIQAEDESAK LCKRRIEHLK EHSSDQPAAA SVWKRKRMDR MMVEHLLRCG YYNTAVKLAR QSGIEDLVNI EMFLTAKEVE ESLERRETAT CLAWCHDNKS RLRKMKSCLE FSLRIQEFIE LIRQNKRLDA VRHARKHFSQ AEGSQLDEVR QAMGMLAFPP DTHISPYKDL LDPARWRMLI QQFRYDNYRL HQLGNNSVFT LTLQAGLSAI KTPQCYKEDG SSKSPDCPVC SRSLNKLAQP LPMAHCANSR LVCKISGDVM NENNPPMMLP NGYVYGYNSL LSIRQDDKVV CPRTKEVFHF SQAEKVYIM
    • Molecular weight
      48 kDa including tags
    • Amino acids
      1 to 396
    • Tags
      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab167902 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity
    > 85 % SDS-PAGE.

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 6.01% Urea, 0.32% Tris HCl, 10% Glycerol

General Info

  • Alternative names
    • 1110030D19Rik
    • Cell proliferation inducing gene 5 protein
    • Cell proliferation-inducing gene 5 protein
    • EMLP
    • EMP
    • Erythroblast macrophage protein
    • GID complex subunit 9 FYV10 homolog
    • GID9
    • HLC 10
    • HLC-10
    • HLC10
    • Human lung cancer oncogene 10 protein
    • Lung cancer related protein 10
    • Macrophage erythroblast attacher
    • MAEA
    • MAEA_HUMAN
    • MGC93683
    • PIG5
    • Proliferation inducing gene 5
    see all
  • Function
    Plays a role in erythroblast enucleation and in the development of the mature macrophages. Mediates the attachment of erythroid cell to mature macrophages, in correlation with the presence of MAEA at cell surface of mature macrophages; This MAEA-mediated contact inhibits erythroid cells apoptosis. Participates to erythroblastic island formation, which is the functional unit of definitive erythropoiesis. Associates with F-actin to regulate actin distribution in erythroblasts and macrophages. May contribute to nuclear architecture and cells division events.
  • Tissue specificity
    Ubiquitous.
  • Sequence similarities
    Contains 1 CTLH domain.
    Contains 1 LisH domain.
  • Developmental stage
    Localized with condensed chromatin at prophase; Detected in nuclear spindle poles at metaphase and in the contractile ring during telophase and cytokinesis.
  • Cellular localization
    Nucleus matrix. Cell membrane. Cytoplasm, cytoskeleton. Localized as nuclear speckled-like pattern.
  • Information by UniProt

Images

  • 15% SDS-PAGE analysis of 3µg ab167902.

References

ab167902 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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