Recombinant Human MAGEA1 protein (Tagged) (ab267887)
Key features and details
- Expression system: Mammalian
- Purity: > 90% SDS-PAGE
- Suitable for: SDS-PAGE
Description
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Product name
Recombinant Human MAGEA1 protein (Tagged)
See all MAGEA1 proteins and peptides -
Purity
> 90 % SDS-PAGE.
NULL -
Expression system
Mammalian -
Accession
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Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
MSLEQRSLHCKPEEALEAQQEALGLVCVQAATSSSSPLVLGTLEEVPTAG STDPPQSPQGASAFPTTINFTRQRQPSEGSSSREEEGPSTSCILESLFRA VITKKVADLVGFLLLKYRAREPVTKAEMLESVIKNYKHCFPEIFGKASES LQLVFGIDVKEADPTGHSYVLVTCLGLSYDGLLGDNQIMPKTGFLIIVLV MIAMEGGHAPEEEIWEELSVMEVYDGREHSAYGEPRKLLTQDLVQEKYLE YRQVPDSDPARYEFLWGPRALAETSYVKVLEYVIKVSARVRFFFPSLREA ALREEEEGV -
Predicted molecular weight
34 kDa -
Amino acids
1 to 309 -
Additional sequence information
N-terminal Flag-Myc-tagged
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Associated products
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Related Products
Specifications
Our Abpromise guarantee covers the use of ab267887 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
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Form
Liquid -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 7.2
Constituents: PBS, 6% Trehalose
Lyophilized from.
General Info
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Alternative names
- Antigen MZ2 E
- Antigen MZ2-E
- Cancer/testis antigen 1.1
see all -
Function
May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes. -
Tissue specificity
Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes. Never expressed in kidney tumors, leukemias and lymphomas. -
Sequence similarities
Contains 1 MAGE domain. -
Cellular localization
Cytoplasm. Nucleus. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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Datasheet download
References (0)
ab267887 has not yet been referenced specifically in any publications.