Recombinant Human MAGEA10 protein (ab158845)
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Overview
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Product nameRecombinant Human MAGEA10 protein
See all MAGEA10 proteins and peptides -
Protein lengthFull length protein
Description
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NatureRecombinant
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SourceWheat germ
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Amino Acid Sequence
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SpeciesHuman
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SequenceMPRAPKRQRCMPEEDLQSQSETQGLEGAQAPLAVEEDASSSTSTSSSFPS SFPSSSSSSSSSCYPLIPSTPEEVSADDETPNPPQSAQIACSSPSVVASL PLDQSDEGSSSQKEESPSTLQVLPDSESLPRSEIDEKVTDLVQFLLFKYQ MKEPITKAEILESVIKNYEDHFPLLFSEASECMLLVFGIDVKEVDPTGHS FVLVTSLGLTYDGMLSDVQSMPKTGILILILSIIFIEGYCTPEEVIWEAL NMMGLYDGMEHLIYGEPRKLLTQDWVQENYLEYRQVPGSDPARYEFLWGP RAHAEIRKMSLLKFLAKVNGSDPRSFPLWYEEALKDEEERAQDRIATTDD TTAMASASSSATGSFSYPE
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Amino acids1 to 369
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Tagsproprietary tag N-Terminus
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Specifications
Our Abpromise guarantee covers the use of ab158845 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
Western blot
ELISA
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FormLiquid
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Additional notesProtein concentration is above or equal to 0.05 mg/ml.
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
General Info
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Alternative names
- Cancer/testis antigen 1.10
- cancer/testis antigen family 1, member 10
- CT1.10
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RelevanceThis gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. MAGEA10 contains one MAGE domain. Its function is not known, though it may play a role in embryonal development and tumor transformation or aspects of tumor progression. MAGEA10 is expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes and placenta.
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Datasheets and documents
References
ab158845 has not yet been referenced specifically in any publications.