Description

  • Product name

    Recombinant Human MANBA protein
  • Expression system

    Wheat germ
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MRLHLLLLLALCGAGTTAAELSYSLRGNWSICNGNGSLELPGAVPGCVHS ALFQQGLIQDSYYRFNDLNYRWVSLDNWTYSKEFKIPFEISKWQKVNLIL EGVDTVSKILFNEVTIGETDNMFNRYSFDITNVVRDVNSIELRFQSAVLY AAQQSKAHTRYQVPPDCPPLVQKGECHVNFVRKEQCSFSWDWGPSFPTQG IWKDVRIEAYNICHLNYFTFSPIYDKSAQEWNLEIESTFDVVSSKPVGGQ VIVAIPKLQTQQTYSIELQPGKRIVELFVNISKNITVETWWPHGHGNQTG YNMTVLFELDGGLNIEKSAKVYFRTVELIEEPIKGSPGLSFYFKINGFPI FLKGSNWIPADSFQDRVTSELLRLLLQSVVDANMNTLRVWGGGIYEQDEF YELCDELGIMVWQDFMFACALYPTDQGFLDSVTAEVAYQIKRLKSHPSII IWSGNNENEEALMMNWYHISFTDRPIYIKDYVTLYVKNIRELVLAGDKSR PFITSSPTNGAETVAEAWVSQNPNSNYFGDVHFYDYISDCWNWKVFPKAR FASEYGYQSWPSFSTLEKVSSTEDWSFNSKFSLHRQHHEGGNKQMLYQAG LHFKLPQSTDPLRTFKDTIYLTQVMQAQCVKTETEFYRRSRSEIVDQQGH TMGALYWQLNDIWQAPSWASLEYGGKWKMLHYFAQNFFAPLLPVGFENEN MFYIYGVSDLHSDYSMTLSVRVHTWSSLEPVCSRVTERFVMKGGEAVCLY EEPVSELLRRCGNCTRESCVVSFYLSADHELLSPTNYHFLSSPKEAVGLC KAQITAIISQQGDIFVFDLETSAVAPFVWLDVGSIPGRFSDNGFLMTEKT RTILFYPWEPTSKNELEQSFHVTSLTDIY
    • Amino acids

      1 to 879
    • Tags

      GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab158857 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Western blot

  • Form

    Liquid
  • Additional notes

    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • Beta-mannosidase
    • GC04M103771
    • Lysosomal beta A mannosidase
    • Manba
    • MANBA_HUMAN
    • Mannanase
    • Mannase
    see all
  • Function

    Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of all N-linked glycoprotein oligosaccharides.
  • Pathway

    Glycan metabolism; N-glycan degradation.
  • Involvement in disease

    Defects in MANBA are the cause of a mild disorder that affects peripheral and central nervous system myelin.
    Mannosidosis, beta A, lysosomal
  • Sequence similarities

    Belongs to the glycosyl hydrolase 2 family.
  • Cellular localization

    Lysosome.
  • Information by UniProt

Images

  • ab158857 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab158857 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab158857.
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