Recombinant Human MAP1 protein (denatured) (ab176051)

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Description

  • Product name

    Recombinant Human MAP1 protein (denatured)

  • Purity

    > 85 % SDS-PAGE.

  • Expression system

    Escherichia coli

  • Accession

    Q96BY2

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      MTLRLLEDWCRGMDMNPRKALLIAGISQSCSVAEIEEALQAGLAPLGEYR LLGRMFRRDENRKVALVGLTAETSHALVPKEIPGKGGIWRVIFKPPDPDN TFLSRLNEFLAGEGMTVGEL SRALGHENGSLDPEQGMIPEMWAPMLAQ ALEALQPALQCLKYKKLRVFSGRESPEPGEEEFGRWMFHTTQMIKAWQVP DVEKRRRLLESLRGPALDVIRVLKINNPLITVDECLQALEEVFGVTDNPR ELQVKYLTTYQKDEEKLSAYVLRLEPLLQKLVQRGAIERDAVNQARLDQV IAGAVHKTIRRELNLPEDGPAPGFLQLLVLIKDYEAAEEEEALLQAILEG NFT

    • Predicted molecular weight

      42 kDa including tags

    • Amino acids

      1 to 351

    • Tags

      His tag N-Terminus

    • Additional sequence information

      NP_071434

  • Description

    Recombinant Human MAP1 protein

Specifications

Our Abpromise guarantee covers the use of ab176051 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Information available upon request.

General Info

  • Alternative names

    • MAP 1
    • MAP-1
    • MAP1
    • MOAP1
    • MOAP1_HUMAN
    • Modulator of Apoptosis
    • Modulator of apoptosis 1
    • Paraneoplastic antigen like 4
    • Paraneoplastic antigen Ma4
    • paraneoplastic Ma antigen family member 4
    • PNMA4
    see all

  • Function

    Required for death receptor-dependent apoptosis. When associated with RASSF1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation.

  • Tissue specificity

    Ubiquitously expressed with higher levels in heart and brain.

  • Sequence similarities

    Belongs to the PNMA family.

  • Domain

    The BH3-like domain is required for association with BAX and for mediating apoptosis. The three BH domains (BH1, BH2, and BH3) of BAX are all required for mediating protein-protein interaction.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human MAP1 protein (denatured) (ab176051)
    SDS-PAGE - Recombinant Human MAP1 protein (denatured) (ab176051)

    15% SDS-PAGE analysis of ab176051 (3μg).

References

ab176051 has not yet been referenced specifically in any publications.

Publishing research using ab176051? Please let us know so that we can cite the reference in this datasheet.

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