Recombinant Human MAP1 protein (denatured) (ab176051)

Product name

Recombinant Human MAP1 protein (denatured)
See all MAP1 proteins and peptides
Protein length

Full length protein
Description

Recombinant Human MAP1 protein

Our Abpromise guarantee covers the use of ab176051 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Stability and Storage

Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

Information available upon request.

Alternative names
- MAP 1
- MAP-1
- MAP1
- MOAP1
- MOAP1_HUMAN
- Modulator of Apoptosis
- Modulator of apoptosis 1
- Paraneoplastic antigen like 4
- Paraneoplastic antigen Ma4
- paraneoplastic Ma antigen family member 4
- PNMA4
see all
Function

Required for death receptor-dependent apoptosis. When associated with RASSF1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation.
Tissue specificity

Ubiquitously expressed with higher levels in heart and brain.
Sequence similarities

Belongs to the PNMA family.
Domain

The BH3-like domain is required for association with BAX and for mediating apoptosis. The three BH domains (BH1, BH2, and BH3) of BAX are all required for mediating protein-protein interaction.
Target information above from: UniProt accession Q96BY2 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt

SDS-PAGE - Recombinant Human MAP1 protein (denatured) (ab176051)

15% SDS-PAGE analysis of ab176051 (3μg).

ab176051 has not yet been referenced specifically in any publications.

Publishing research using ab176051? Please let us know so that we can cite the reference in this datasheet.

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