Recombinant Human MAP1 protein (denatured) (ab176051)

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SDS-PAGE - Recombinant Human MAP1 protein (denatured) (ab176051)

    Key features and details

    • Expression system: Escherichia coli
    • Purity: > 85% SDS-PAGE
    • Tags: His tag N-Terminus
    • Suitable for: SDS-PAGE

    Description

    • Product name

      Recombinant Human MAP1 protein (denatured)

    • Purity

      > 85 % SDS-PAGE.

    • Expression system

      Escherichia coli

    • Accession

      Q96BY2

    • Protein length

      Full length protein

    • Animal free

      No

    • Nature

      Recombinant

      • Species

        Human

      • Sequence

        MTLRLLEDWCRGMDMNPRKALLIAGISQSCSVAEIEEALQAGLAPLGEYR LLGRMFRRDENRKVALVGLTAETSHALVPKEIPGKGGIWRVIFKPPDPDN TFLSRLNEFLAGEGMTVGEL SRALGHENGSLDPEQGMIPEMWAPMLAQ ALEALQPALQCLKYKKLRVFSGRESPEPGEEEFGRWMFHTTQMIKAWQVP DVEKRRRLLESLRGPALDVIRVLKINNPLITVDECLQALEEVFGVTDNPR ELQVKYLTTYQKDEEKLSAYVLRLEPLLQKLVQRGAIERDAVNQARLDQV IAGAVHKTIRRELNLPEDGPAPGFLQLLVLIKDYEAAEEEEALLQAILEG NFT

      • Predicted molecular weight

        42 kDa including tags

      • Amino acids

        1 to 351

      • Tags

        His tag N-Terminus

      • Additional sequence information

        NP_071434

    • Description

      Recombinant Human MAP1 protein

    Specifications

    Our Abpromise guarantee covers the use of ab176051 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

    • Form

      Liquid
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      pH: 8.00
      Constituents: 0.32% Tris-HCl buffer, 2.4% Urea, 10% Glycerol (glycerin, glycerine)

    General Info

    • Alternative names

      • MAP 1
      • MAP-1
      • MAP1
      • MOAP1
      • MOAP1_HUMAN
      • Modulator of Apoptosis
      • Modulator of apoptosis 1
      • Paraneoplastic antigen like 4
      • Paraneoplastic antigen Ma4
      • paraneoplastic Ma antigen family member 4
      • PNMA4
      see all

    • Function

      Required for death receptor-dependent apoptosis. When associated with RASSF1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation.

    • Tissue specificity

      Ubiquitously expressed with higher levels in heart and brain.

    • Sequence similarities

      Belongs to the PNMA family.

    • Domain

      The BH3-like domain is required for association with BAX and for mediating apoptosis. The three BH domains (BH1, BH2, and BH3) of BAX are all required for mediating protein-protein interaction.
    • Information by UniProt

    Images

    • SDS-PAGE - Recombinant Human MAP1 protein (denatured) (ab176051)
      SDS-PAGE - Recombinant Human MAP1 protein (denatured) (ab176051)

      15% SDS-PAGE analysis of ab176051 (3μg).

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab176051? Please let us know so that we can cite the reference in this datasheet.

    ab176051 has not yet been referenced specifically in any publications.

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