Recombinant Human MAP1 protein (denatured) (ab176051)

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Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
      Q96BY2
    • Species
      Human
    • Sequence
      MTLRLLEDWCRGMDMNPRKALLIAGISQSCSVAEIEEALQAGLAPLGEYR LLGRMFRRDENRKVALVGLTAETSHALVPKEIPGKGGIWRVIFKPPDPDN TFLSRLNEFLAGEGMTVGEL SRALGHENGSLDPEQGMIPEMWAPMLAQ ALEALQPALQCLKYKKLRVFSGRESPEPGEEEFGRWMFHTTQMIKAWQVP DVEKRRRLLESLRGPALDVIRVLKINNPLITVDECLQALEEVFGVTDNPR ELQVKYLTTYQKDEEKLSAYVLRLEPLLQKLVQRGAIERDAVNQARLDQV IAGAVHKTIRRELNLPEDGPAPGFLQLLVLIKDYEAAEEEEALLQAILEG NFT
    • Molecular weight
      42 kDa including tags
    • Amino acids
      1 to 351
    • Tags
      His tag N-Terminus
    • Additional sequence information
      NP_071434

Specifications

Our Abpromise guarantee covers the use of ab176051 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity
    > 85 % SDS-PAGE.

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Information available upon request.

General Info

  • Alternative names
    • MAP 1
    • MAP-1
    • MAP1
    • MOAP1
    • MOAP1_HUMAN
    • Modulator of Apoptosis
    • Modulator of apoptosis 1
    • Paraneoplastic antigen like 4
    • Paraneoplastic antigen Ma4
    • paraneoplastic Ma antigen family member 4
    • PNMA4
    see all
  • Function
    Required for death receptor-dependent apoptosis. When associated with RASSF1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation.
  • Tissue specificity
    Ubiquitously expressed with higher levels in heart and brain.
  • Sequence similarities
    Belongs to the PNMA family.
  • Domain
    The BH3-like domain is required for association with BAX and for mediating apoptosis. The three BH domains (BH1, BH2, and BH3) of BAX are all required for mediating protein-protein interaction.
  • Information by UniProt

Images

  • SDS-PAGE - Human MAP1 full length protein (ab176051)
    SDS-PAGE - Human MAP1 full length protein (ab176051)

    15% SDS-PAGE analysis of ab176051 (3μg).

References

ab176051 has not yet been referenced specifically in any publications.

Publishing research using ab176051? Please let us know so that we can cite the reference in this datasheet.

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