Overview

Description

  • Nature

    Recombinant
  • Source

    Wheat germ
  • Amino Acid Sequence
    • Species

      Human
    • Sequence

      MEAPLRPAADILRRNPQQDYELVQRVGSGTYGDVYKARNVHTGELAAVKI IKLEPGDDFSLIQQEIFMVKECKHCNIVAYFGSYLSREKLWICMEYCGGG SLQDIYHVTGPLSELQIAYVCRETLQGLAYLHTKGKMHRDIKGANILLTD HGDVKLADFGVAAKITATIAKRKSFIGTPYWMAPEVAAVEKNGGYNQLCD IWAVGITAIELGELQPPMFDLHPMRALFLMSKSNFQPPKLKDKTKWSSTF HNFVKIALTKNPKKRPTAERLLTHTFVAQPGLSRALAVELLDKVNNPDNH AHYTEADDDDFEPHAIIRHTIRSTNRNARAERTASEINFDKLQFEPPLRK ETEARDEMGLSSDPNFMLQWNPFVDGANTGKSTSKRAIPPPLPPKPRISS YPEDNFPDEEKASTIKHCPDSESRAPQILRRQSSPSCGPVAETSSIGNGD GISKLMSENTEGSAQAPQLPRKKDKRDFPKPAINGLPPTPKVLMGACFSK VFDGCPLKINCATSWIHPDTKDQYIIFGTEDGIYTLNLNELHEATMEQLF PRKCTWLYVINNTLMSLSEGKTFQLYSHNLIALFEHAKKPGLAAHIQTHR FPDRILPRKFALTTKIPDTKGCHKCCIVRNPYTGHKYLCGALQSGIVLLQ WYEPMQKFMLIKHFDFPLPSPLNVFEMLVIPEQEYPMVCVAISKGTESNQ VVQFETINLNSASSWFTEIGAGSQQLDSIHVTQLERDTVLVCLDKFVKIV NLQGKLKSSKKLASELSFDFRIESVVCLQDSVLAFWKHGMQGKSFKSDEV TQEISDETRVFRLLGSDRVVVLESRPTENPTAHSNLYILAGHENSY
    • Amino acids

      1 to 846
    • Tags

      GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab161342 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

  • Form

    Liquid
  • Additional notes

    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • EC 2.7.11.1
    • KHS
    • Kinase homologous to SPS1/STE20
    • MAPK/ERK kinase kinase kinase 5
    • MEK kinase kinase 5
    • MEKKK 5
    see all
  • Relevance

    MAP4K5, a member of the STE20 subfamily of Ser/Thr protein kinases, may play a role in the response to environmental stress. It appears to act upstream of the JUN N-terminal pathway. MAP4K5 interacts with both SH3 domains of the adapter proteins CRK and CRKL. This cytoplasmic protein is ubiquitously expressed in all tissues examined, with high levels in the ovary, testis and prostate.
  • Cellular localization

    Cytoplasmic

Images

  • ab161342 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab161342 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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