Recombinant human MAPK11 protein (ab125663)
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- References
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Description
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Product name
Recombinant human MAPK11 protein
See all MAPK11 proteins and peptides -
Biological activity
The specific activity of ab125663 was determined to be 780 nmol/min/mg. -
Purity
> 95 % Densitometry.
Purity was determined to be >95% by densitometry. -
Expression system
Baculovirus infected Sf9 cells -
Accession
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Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Predicted molecular weight
71 kDa including tags -
Amino acids
1 to 364
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Associated products
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Related Products
Specifications
Our Abpromise guarantee covers the use of ab125663 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
Western blot
Functional Studies
SDS-PAGE
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Form
Liquid -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 7.50
Constituents: 0.31% Glutathione, 0.002% PMSF, 0.004% DTT, 0.79% Tris HCl, 0.003% EDTA, 25% Glycerol, 0.88% Sodium chlorideThis product is an active protein and may elicit a biological response in vivo, handle with caution.
General Info
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Alternative names
- Human p38Beta MAP kinase mRNA complete cds
- MAP kinase 11
- MAP kinase p38 beta
see all -
Function
Kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment, by cytokines, or by environmental stress. Phosphorylates preferentially transcription factor ATF2. -
Tissue specificity
Highest levels in the brain and heart. Also expressed in the placenta, lung, liver, skeletal muscle, kidney and pancreas. -
Sequence similarities
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
Contains 1 protein kinase domain. -
Domain
The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases. -
Post-translational
modificationsDually phosphorylated on Thr-180 and Tyr-182, which activates the enzyme. - Information by UniProt
Images
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Functional Studies - Recombinant human MAPK11 protein (ab125663)The specific activity of ab125663 was determined to be 780 nmol/min/mg by Kinase Assay. -
SDS-PAGE - Recombinant human MAPK11 protein (ab125663)SDS-PAGE analysis of ab125663.
Datasheets and documents
References
ab125663 has not yet been referenced specifically in any publications.
