Recombinant human MAPK11 protein (ab125663)
Key features and details
- Expression system: Baculovirus infected Sf9 cells
- Purity: > 95% Densitometry
- Active: Yes
- Suitable for: WB, Functional Studies, SDS-PAGE
Description
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Product name
Recombinant human MAPK11 protein
See all MAPK11 proteins and peptides -
Biological activity
The specific activity of ab125663 was determined to be 780 nmol/min/mg. -
Purity
> 95 % Densitometry.
Purity was determined to be >95% by densitometry. -
Expression system
Baculovirus infected Sf9 cells -
Accession
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Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Predicted molecular weight
71 kDa including tags -
Amino acids
1 to 364
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Specifications
Our Abpromise guarantee covers the use of ab125663 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
Western blot
Functional Studies
SDS-PAGE
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Form
Liquid -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 7.50
Constituents: 0.31% Glutathione, 0.002% PMSF, 0.004% DTT, 0.79% Tris HCl, 0.003% EDTA, 25% Glycerol (glycerin, glycerine), 0.88% Sodium chlorideThis product is an active protein and may elicit a biological response in vivo, handle with caution.
General Info
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Alternative names
- Human p38Beta MAP kinase mRNA complete cds
- MAP kinase 11
- MAP kinase p38 beta
see all -
Function
Kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment, by cytokines, or by environmental stress. Phosphorylates preferentially transcription factor ATF2. -
Tissue specificity
Highest levels in the brain and heart. Also expressed in the placenta, lung, liver, skeletal muscle, kidney and pancreas. -
Sequence similarities
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
Contains 1 protein kinase domain. -
Domain
The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases. -
Post-translational
modificationsDually phosphorylated on Thr-180 and Tyr-182, which activates the enzyme. - Information by UniProt
Images
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Functional Studies - Recombinant human MAPK11 protein (ab125663)The specific activity of ab125663 was determined to be 780 nmol/min/mg by Kinase Assay. -
SDS-PAGE - Recombinant human MAPK11 protein (ab125663)SDS-PAGE analysis of ab125663.
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
References (0)
ab125663 has not yet been referenced specifically in any publications.
