Recombinant Human MARCH3 protein (ab165062)

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Overview

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      MTTSRCSHLPEVLPDCTSSAAPVVKTVEDCGSLVNGQPQYVMQVSAKDGQ LLSTVVRTLATQSPFNDRPMCRICHEGSSQEDLLSPCECTGTLGTIHRSC
    • Amino acids
      1 to 100
    • Tags
      proprietary tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab165062 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Western blot

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • E3 ubiquitin protein ligase MARCH3
    • E3 ubiquitin-protein ligase MARCH3
    • FLJ20096
    • March 3
    • MARCH III
    • MARCH-III
    • March3
    • MARH3_HUMAN
    • Membrane associated RING CH protein III
    • Membrane associated ring finger (C3HC4) 3
    • Membrane associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase
    • Membrane associated RING finger protein 3
    • Membrane-associated RING finger protein 3
    • Membrane-associated RING-CH protein III
    • MGC48332
    • RING finger protein 173
    • RNF173
    see all
  • Function
    E3 ubiquitin-protein ligase which may be involved in endosomal trafficking. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
  • Pathway
    Protein modification; protein ubiquitination.
  • Sequence similarities
    Contains 1 RING-CH-type zinc finger.
  • Domain
    The RING-CH-type zinc finger domain is required for E3 ligase activity.
  • Cellular localization
    Cytoplasmic vesicle membrane. Early endosome membrane.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human MARCH3 protein (ab165062)
    SDS-PAGE - Recombinant Human MARCH3 protein (ab165062)
    ab165062 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab165062 has not yet been referenced specifically in any publications.

Publishing research using ab165062? Please let us know so that we can cite the reference in this datasheet.

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