Overview

Description

  • Nature

    Recombinant
  • Source

    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species

      Human
    • Sequence

      MPEMPEDMEQ EEVNIPNRRV LVTGATGLLG RAVHKEFQQN NWHAVGCGFR RARPKFEQVN LLDSNAVHHI IHDFQPHVIV HCAAERRPDV VENQPDAASQ LNVDASGNLA KEAAAVGAFL IYISSDYVFD GTNPPYREED IPAPLNLYGK TKLDGEKAVL ENNLGAAVLR IPILYGEVEK LEESAVTVMF DKVQFSNKSA NMDHWQQRFP THVKDVATVC RQLAEKRMLD PSIKGTFHWS GNEQMTKYEM ACAIADAFNL PSSHLRPITD SPVLGAQRPR NTQLDCSKLE TLGIGQRTPF RIGIKESLWP FLIDKRWRQT VFH.
    • Molecular weight

      36 kDa
    • Amino acids

      1 to 323
    • Additional sequence information

      Recombinant Human MAT2B produced in E.Coli is a single, non-glycosylated polypeptide chain containing 323 amino acids (1-323 a.a).

Specifications

Our Abpromise guarantee covers the use of ab117699 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity

    > 90 % SDS-PAGE.
    ab117699 is purified by conventional chromatography techniques.
  • Form

    Liquid
  • Additional notes

    For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 0.02% DTT, 0.03% EDTA, 10% Glycerol

General Info

  • Alternative names

    • 1110064C04Rik
    • 2410018D16Rik
    • AI182287
    • AU022853
    • Beta regulatory subunit of methionine adenosyltransferase
    • dTDP 4 keto 6 deoxy D glucose 4 reductase
    • DTDP-4-keto-6-deoxy-D-glucose 4-reductase
    • MAT II
    • MAT II beta
    • Mat2b
    • MAT2B_HUMAN
    • MATIIbeta
    • Methionine adenosyltransferase 2 beta subunit
    • Methionine adenosyltransferase 2 subunit beta
    • Methionine adenosyltransferase II beta
    • MGC12237
    • MSTP045
    • Nbla02999
    • OTTMUSP00000005600
    • Putative dTDP-4-keto-6-deoxy-D-glucose 4-reductase
    • Putative protein product of Nbla02999
    • RP23-382C18.2
    • SDR23E1
    • Short chain dehydrogenase/reductase family 23E member 1
    • TGR
    see all
  • Function

    Non-catalytic regulatory subunit of S-adenosylmethionine synthetase 2 (MAT2A), an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates the activity of S-adenosylmethionine synthetase 2 by changing its kinetic properties, rendering the enzyme more susceptible to S-adenosylmethionine inhibition.
  • Tissue specificity

    Widely expressed.
  • Pathway

    Amino-acid biosynthesis; S-adenosyl-L-methionine biosynthesis; S-adenosyl-L-methionine from L-methionine: step 1/1.
  • Sequence similarities

    Belongs to the dTDP-4-dehydrorhamnose reductase family. MAT2B subfamily.
  • Information by UniProt

References

ab117699 has not yet been referenced specifically in any publications.

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