Recombinant Human Matrin 3 protein (ab153017)

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SDS-PAGE - Recombinant Human Matrin 3 protein (ab153017)

    Key features and details

    • Expression system: Wheat germ
    • Tags: GST tag N-Terminus
    • Suitable for: WB, ELISA

    Description

    • Product name

      Recombinant Human Matrin 3 protein

    • Expression system

      Wheat germ

    • Protein length

      Full length protein

    • Animal free

      No

    • Nature

      Recombinant

      • Species

        Human

      • Sequence

        MSKSFQQSSLSRDSQGHGRDLSAAGIGLLAAATQSLSMPASLGRMNQGTA RLASLMNLGMSSSLNQQGAHSALSSASTSSHNLQSIFNIGSRGPLPLSSQ HRGDADQASNILASFGLSARDLDELSRYPEDKITPENLPQILLQLKRRRT EEGPTLSYGRDGRSATREPPYRVPRDDWEEKRHFRRDSFDDRGPSLNPVL DYDHGSRSQESGYYDRMDYEDDRLRDGERCRDDSFFGETSHNYHKFDSEY ERMGRGPGPLQERSLFEKKRGAPPSSNIEDFHGLLPKGYPHLCSICDLPV HSNKEWSQHINGASHSRRCQLLLEIYPEWNPDNDTGHTMGDPFMLQQSTN PAPGILGPPPPSFHLGGPAVGPRGNLGAGNGNLQGPRHMQKGRVETSRVV HIMDFQRGKNLRYQLLQLVEPFGVISNHLILNKINEAFIEMATTEDAQAA VDYYTTTPALVFGKPVRVHLSQKYKRIKKPEGKPDQKFDQKQELGRVIHL SNLPHSGYSDSAVLKLAEPYGKIKNYILMRMKSQAFIEMETREDAMAMVD HCLKKALWFQGRCVKVDLSEKYKKLVLRIPNRGIDLLKKDKSRKRSYSPD GKESPSDKKSKTDGSQKTESSTEGKEQEEKSGEDGEKDTKDDQTEQEPNM LLESEDELLVDEEEAAALLESGSSVGDETDLANLGDVASDGKKEPSDKAV KKDGSASAAAKKKLKKVDKIEELDQENEAALENGIKNEENTEPGAESSEN ADDPNKDTSENADGQSDENKDDYTIPDEYRIGPYQPNVPVGIDYVIPKTG FYCKLCSLFYTNEEVAKNTHCSSLPHYQKLKKFLNKLAEERRQKKET

      • Amino acids

        1 to 847

      • Tags

        GST tag N-Terminus

    Specifications

    Our Abpromise guarantee covers the use of ab153017 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      Western blot

      ELISA

    • Form

      Liquid

    • Additional notes

       

       

    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

      pH: 8.00
      Constituents: 0.31% Glutathione, 0.79% Tris HCl

    General Info

    • Alternative names

      • ALS21
      • KIAA0723
      • Matr3
      • MATR3_HUMAN
      • Matrin-3
      • Matrin3
      • MPD2
      • VCPDM
      • Vocal cord and pharyngeal weakness with distal myopathy
      see all

    • Function

      May play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. In association with the SFPQ-NONO heteromer may play a role in nuclear retention of defective RNAs.

    • Involvement in disease

      Defects in MATR3 are the cause of myopathy distal type 2 (MPD2) [MIM:606070]; also called vocal cord and pharyngeal dysfunction with distal myopathy (VCPDM). MPD2 is a muscular disorder characterized by distal weakness, with onset in hands and feet, associated with vocal cord and pharyngeal weakness causing a nasal voice and swallowing disorders.

    • Sequence similarities

      Contains 1 matrin-type zinc finger.
      Contains 2 RRM (RNA recognition motif) domains.

    • Cellular localization

      Nucleus matrix.
    • Information by UniProt

    Images

    • SDS-PAGE - Recombinant Human Matrin 3 protein (ab153017)
      SDS-PAGE - Recombinant Human Matrin 3 protein (ab153017)
      ab153017 on a 12.5% SDS-PAGE stained with Coomassie Blue.

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab153017? Please let us know so that we can cite the reference in this datasheet.

    ab153017 has not yet been referenced specifically in any publications.

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