Recombinant Human Matrin 3 protein (ab153017)

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Description

  • Product name

    Recombinant Human Matrin 3 protein

  • Expression system

    Wheat germ

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      MSKSFQQSSLSRDSQGHGRDLSAAGIGLLAAATQSLSMPASLGRMNQGTA RLASLMNLGMSSSLNQQGAHSALSSASTSSHNLQSIFNIGSRGPLPLSSQ HRGDADQASNILASFGLSARDLDELSRYPEDKITPENLPQILLQLKRRRT EEGPTLSYGRDGRSATREPPYRVPRDDWEEKRHFRRDSFDDRGPSLNPVL DYDHGSRSQESGYYDRMDYEDDRLRDGERCRDDSFFGETSHNYHKFDSEY ERMGRGPGPLQERSLFEKKRGAPPSSNIEDFHGLLPKGYPHLCSICDLPV HSNKEWSQHINGASHSRRCQLLLEIYPEWNPDNDTGHTMGDPFMLQQSTN PAPGILGPPPPSFHLGGPAVGPRGNLGAGNGNLQGPRHMQKGRVETSRVV HIMDFQRGKNLRYQLLQLVEPFGVISNHLILNKINEAFIEMATTEDAQAA VDYYTTTPALVFGKPVRVHLSQKYKRIKKPEGKPDQKFDQKQELGRVIHL SNLPHSGYSDSAVLKLAEPYGKIKNYILMRMKSQAFIEMETREDAMAMVD HCLKKALWFQGRCVKVDLSEKYKKLVLRIPNRGIDLLKKDKSRKRSYSPD GKESPSDKKSKTDGSQKTESSTEGKEQEEKSGEDGEKDTKDDQTEQEPNM LLESEDELLVDEEEAAALLESGSSVGDETDLANLGDVASDGKKEPSDKAV KKDGSASAAAKKKLKKVDKIEELDQENEAALENGIKNEENTEPGAESSEN ADDPNKDTSENADGQSDENKDDYTIPDEYRIGPYQPNVPVGIDYVIPKTG FYCKLCSLFYTNEEVAKNTHCSSLPHYQKLKKFLNKLAEERRQKKET

    • Amino acids

      1 to 847

    • Tags

      GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab153017 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

  • Form

    Liquid

  • Additional notes

     

     

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • ALS21
    • KIAA0723
    • Matr3
    • MATR3_HUMAN
    • Matrin-3
    • Matrin3
    • MPD2
    • VCPDM
    • Vocal cord and pharyngeal weakness with distal myopathy
    see all

  • Function

    May play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. In association with the SFPQ-NONO heteromer may play a role in nuclear retention of defective RNAs.

  • Involvement in disease

    Defects in MATR3 are the cause of myopathy distal type 2 (MPD2) [MIM:606070]; also called vocal cord and pharyngeal dysfunction with distal myopathy (VCPDM). MPD2 is a muscular disorder characterized by distal weakness, with onset in hands and feet, associated with vocal cord and pharyngeal weakness causing a nasal voice and swallowing disorders.

  • Sequence similarities

    Contains 1 matrin-type zinc finger.
    Contains 2 RRM (RNA recognition motif) domains.

  • Cellular localization

    Nucleus matrix.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human Matrin 3 protein (ab153017)
    SDS-PAGE - Recombinant Human Matrin 3 protein (ab153017)
    ab153017 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab153017 has not yet been referenced specifically in any publications.

Publishing research using ab153017? Please let us know so that we can cite the reference in this datasheet.

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