Overview

  • Product name

    Recombinant Human MCM4 protein
  • Protein length

    Full length protein

Description

  • Nature

    Recombinant
  • Source

    Wheat germ
  • Amino Acid Sequence
    • Accession
    • Species

      Human
    • Sequence

      MSSPASTPSRRGSRRGRATPAQTPRSEDARSSPSQRRRGEDSTSTGELQP MPTSPGVDLQSPAAQDVLFSSPPQMHSSAIPLDFDVSSPLTYGTPSSRVE GTPRSGVRGTPVRQRPDLGSAQKGLQVDLQSDGAAAEDIVASEQSLGQKL VIWGTDVNVAACKENFQRFLQRFIDPLAKEEENVGIDITEPLYMQRLGEI NVIGEPFLNVNCEHIKSFDKNLYRQLISYPQEVIPTFDMAVNEIFFDRYP DSILEHQIQVRPFNALKTKNMRNLNPEDIDQLITISGMVIRTSQLIPEMQ EAFFQCQVCAHTTRVEMDRGRIAEPSVCGRCHTTHSMALIHNRSLFSDKQ MIKLQESPEDMPAGQTPHTVILFAHNDLVDKVQPGDRVNVTGIYRAVPIR VNPRVSNVKSVYKTHIDVIHYRKTDAKRLHGLDEEAEQKLFSEKRVELLK ELSRKPDIYERLASALAPSIYEHEDIKKGILLQLFGGTRKDFSHTGRGKF RAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVGLTAYVMKD PETRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAK AGIICQLNARTSVLAAANPIESQWNPKKTTIENIQLPHTLLSRFDLIFLM LDPQDEAYDRRLAHHLVALYYQSEEQAEEELLDMAVLKDYIAYAHSTIMP RLSEEASQALIEAYVDMRKIGSSRGMVSAYPRQLESLIRLAEAHAKVRLS NKVEAIDVEEAKRLHREALKQSATDPRTGIVDISILTTGMSATSRKRKEE LAEALKKLILSKGKTPALKYQQLFEDIRGQSDIAITKDMFEEALRALADD DFLTVTGKTVRLL
    • Molecular weight

      123 kDa including tags
    • Amino acids

      1 to 863

Specifications

Our Abpromise guarantee covers the use of ab131916 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Western blot

    SDS-PAGE

  • Form

    Liquid
  • Additional notes

    Protein concentration is above or equal to 0.05 µg/µl
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • 19G
    • AI325074
    • AU045576
    • CDC 21
    • CDC 54
    • CDC21
    • CDC21 homolog
    • CDC21, S. pombe, homolog of
    • CDC54
    • Cell division cycle 21, S. pombe, homolog of
    • DNA replication licensing factor MCM 4
    • DNA replication licensing factor MCM4
    • hCdc 21
    • hCdc21
    • Homolog of S. pombe cell devision cycle 21
    • KIAA4003
    • mcdc21
    • MCM 4
    • MCM 4 minichromosome maintenance deficient 4
    • mcm4
    • MCM4 minichromosome maintenance deficient 4
    • MCM4 minichromosome maintenance deficient 4, mitotin (S. cerevisiae)
    • MCM4_HUMAN
    • Mcmd4
    • MGC33310
    • Minichromosome maintenance 4
    • Minichromosome maintenance complex component 4
    • Minichromosome maintenance deficient (S. cerevisiae) 4
    • Minichromosome maintenance deficient 4
    • Minichromosome maintenance deficient 4 homolog (S. cerevisiae)
    • Minichromosome maintenance, S. cerevisiae, homolog of, 4
    • mKIAA4003
    • NKCD
    • NKGCD
    • P1 CDC21
    • P1-CDC21
    • P1CDC21
    see all
  • Function

    Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
  • Sequence similarities

    Belongs to the MCM family.
    Contains 1 MCM domain.
  • Cellular localization

    Nucleus.
  • Information by UniProt

Images

  • ab131916 on a 12.5% SDS-PAGE Stained with Coomassie Blue.

References

ab131916 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab131916.
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