Recombinant Human MCPIP1 protein (ab127129)

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Description

  • Product name

    Recombinant Human MCPIP1 protein

  • Expression system

    Escherichia coli

  • Accession

    Q5D1E8

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Predicted molecular weight

      29 kDa

    • Amino acids

      234 to 503

Specifications

Our Abpromise guarantee covers the use of ab127129 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20ºC.

    Constituents: 0.32% Tris HCl, 0.58% Sodium chloride

  • Reconstitution
    Reconstitute with water to desired concentration.

General Info

  • Alternative names

    • dJ423B22.1
    • MCP 1 treatment-induced protein
    • MCP-induced protein 1
    • MCP1-induced protein
    • MCPIP
    • MCPIP 1
    • Ribonuclease ZC3H12A
    • RP3-423B22.1
    • ZC12A_HUMAN
    • ZC3H 12A
    • ZC3H12 A
    • Zc3h12a
    • Zinc finger CCCH domain-containing protein 12A
    • Zinc finger CCCH type containing 12A
    see all

  • Function

    Has RNase activity and selectively degrades specific target mRNA species. Modulates the immune response and inflammation by regulating the decay of specific mRNA molecules. Recognizes the 3'-untranslated region (UTR) of the mRNA for IL6, CALCR and IL12B. Required for normal decay of IL6 mRNA (By similarity). Triggers apoptosis and promotes angiogenesis in response to the binding of CCL2 to CCR2. Regulates expression of CDH12 and CHD19.

  • Sequence similarities

    Belongs to the ZC3H12 family.
    Contains 1 C3H1-type zinc finger.

  • Cellular localization

    Cytoplasm. Nucleus.
  • Information by UniProt

References

ab127129 has not yet been referenced specifically in any publications.

Publishing research using ab127129? Please let us know so that we can cite the reference in this datasheet.

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