The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
% SDS-PAGE. ab90707 was purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
pH: 8.00 Constituents: 0.0308% DTT, 0.316% Tris HCl, 10% Glycerol
Colony stimulating factor 1
Colony stimulating factor 1 (macrophage)
Colony stimulating factor macrophage specific
Macrophage colony stimulating factor
Macrophage Colony Stimulating Factor 1
Processed macrophage colony-stimulating factor 1
Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. CSF-1 induces cells of the monocyte/macrophage lineage. It plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy.
Glycosylation and proteolytic cleavage yield different soluble forms. A high molecular weight soluble form is a proteoglycan containing chondroitin sulfate. Isoform 1 is N- and O-glycosylated. Isoform 3 is N-glycosylated.