Recombinant Human MD1 protein (denatured) (ab167887)

Overview

  • Product name
    Recombinant Human MD1 protein (denatured)
    See all MD1 proteins and peptides
  • Protein length
    Full length protein
  • Description
    Recombinant Human MD1 protein

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MGSSHHHHHH SSGLVPRGSH MGSGGGGKAW PTHVVCSDSG LEVLYQSCDP LQDFGFSVEK CSKQLKSNIN IRFGIILRED IKELFLDLAL MSQGSSVLNF SYPICEAALP KFSFCGRRKG EQIYYAGPVN NPEFTIPQGE YQVLLELYTE KRSTVACANA TIMCS
    • Molecular weight
      18 kDa including tags
    • Amino acids
      21 to 162
    • Tags
      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab167887 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity
    > 85 % SDS-PAGE.

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 2.4% Urea, 0.32% Tris HCl, 10% Glycerol

General Info

  • Alternative names
    • BPAD
    • dJ80N2.1
    • Ly 86
    • Ly-86
    • Ly86
    • LY86_HUMAN
    • Lymphocyte antigen 86
    • Lymphocyte antigen 86 precursor
    • Major affective disorder 1
    • MD 1
    • MD1 protein
    • MD1 RP105 associated
    • MMD 1
    • Protein MD 1
    • Protein MD-1
    • RP1-80N2.1
    see all
  • Function
    May cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production. Important for efficient CD180 cell surface expression.
  • Tissue specificity
    Highly expressed in B-cells, monocytes and tonsil.
  • Cellular localization
    Secreted > extracellular space. Associated with CD180 at the cell surface.
  • Information by UniProt

Images

  • 15% SDS-PAGE analysis of ab167887 (3µg).

References

ab167887 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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