Description

  • Product name

    Recombinant Human MED7 protein
  • Purity

    > 85 % SDS-PAGE.
    Purified using conventional chromatography techniques.
  • Expression system

    Escherichia coli
  • Accession

  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MGSSHHHHHH SSGLVPRGSH MGSMGEPQQV SALPPPPMQY IKEYTDENIQ EGLAPKPPPP IKDSYMMFGN QFQCDDLIIR PLESQGIERL HPMQFDHKKE LRKLNMSILI NFLDLLDILI RSPGSIKREE KLEDLKLLFV HVHHLINEYR PHQARETLRV MMEVQKRQRL ETAERFQKHL ERVIEMIQNC LASLPDDLPH SEAGMRVKTE PMDADDSNNC TGQNEHQREN SGHRRDQIIE KDAALCVLID EMNERP
    • Predicted molecular weight

      30 kDa including tags
    • Amino acids

      1 to 233
    • Tags

      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab131673 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry

    MALDI-TOF
  • Form

    Liquid
  • Additional notes

    Previously labelled as CRSP9. 

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 10% Glycerol, 0.58% Sodium chloride

General Info

  • Alternative names

    • Activator recruited cofactor 34 kDa component
    • Activator-recruited cofactor 34 kDa component
    • ARC34
    • Cofactor required for Sp1 transcriptional activation subunit 9
    • Cofactor required for Sp1 transcriptional activation, subunit 9 (33kD)
    • Cofactor required for Sp1 transcriptional activation, subunit 9, 33kDa
    • CRSP complex subunit 9
    • CRSP33
    • CRSP9
    • hMED7
    • MED7
    • MED7_HUMAN
    • Mediator complex subunit 7
    • Mediator of RNA polymerase II transcription subunit 7
    • MGC12284
    • RNA polymerase transcriptional regulation mediator subunit 7 homolog
    • Transcriptional coactivator CRSP33
    see all
  • Function

    Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
  • Sequence similarities

    Belongs to the Mediator complex subunit 7 family.
  • Post-translational
    modifications

    Constitutively sumoylated.
  • Cellular localization

    Nucleus.
  • Information by UniProt

Images

  • 15.5% SDS-PAGE stained with Coomassie Blue showing ab131673 at approximately 29.7 kDa (3µg).

References

ab131673 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab131673.
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