Product nameRecombinant human MEKK2 protein
See all MEKK2 proteins and peptides
Protein lengthFull length protein
SourceBaculovirus infected Sf9 cells
Amino Acid Sequence
Molecular weight97 kDa including tags
Amino acids1 to 619
Our Abpromise guarantee covers the use of ab135009 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Biological activitySpecific Activity: 18 pmol/min/µg. Assay conditions: Enzyme reaction was conducted in a Kinase Buffer (50 mM Tris pH 7.4, 20 mM MgCl2, 0.1 mg/ml BSA and 1mM DTT) containing 20 µM ATP and 0.2 mg/ml poly-(Glu-Tyr) for 30 minutes at 30 °C. Enzyme activity was then measured.
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped on Dry Ice. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.
Constituents: 0.017% Potassium chloride, 0.06% DTT, 0.64% Tris HCl, 20% Glycerol, 0.65% Sodium chloride
This product is an active protein and may elicit a biological response in vivo, handle with caution.
- MAPK/ERK kinase kinase 2
FunctionComponent of a protein kinase signal transduction cascade. Regulates the JNK and ERK5 pathways by phosphorylating and activating MAP2K5 and MAP2K7 (By similarity). Plays a role in caveolae kiss-and-run dynamics.
Sequence similaritiesBelongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
Contains 1 OPR domain.
Contains 1 protein kinase domain.
Cellular localizationCytoplasm. Nucleus. Upon EGF stimulation, translocates into the nucleus.
- Information by UniProt
ab135009 has not yet been referenced specifically in any publications.