Description

  • Product name

    Recombinant Human METTL11A protein (His tag)
  • Purity

    > 95 % SDS-PAGE.
    ab211312 was purified using conventional chromatography techniques.
  • Expression system

    Escherichia coli
  • Accession

  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MGSSHHHHHH SSGLVPRGSH MGSEFMTSEV IEDEKQFYSK AKTYWKQIPP TVDGMLGGYG HISSIDINSS RKFLQRFLRE GPNKTGTSCA LDCGAGIGRI TKRLLLPLFR EVDMVDITED FLVQAKTYLG EEGKRVRNYF CCGLQDFTPE PDSYDVIWIQ WVIGHLTDQH LAEFLRRCKG SLRPNGIIVI KDNMAQEGVI LDDVDSSVCR DLDVVRRIIC SAGLSLLAEE RQENLPDEIY HVYSFALR
    • Predicted molecular weight

      28 kDa including tags
    • Amino acids

      1 to 223
    • Tags

      His tag N-Terminus
    • Additional sequence information

      NP_054783.

Specifications

Our Abpromise guarantee covers the use of ab211312 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8
    Constituents: 0.32% Tris HCl, 0.87% Sodium chloride, 10% Glycerol

General Info

  • Alternative names

    • AD 003
    • Alpha N-terminal protein methyltransferase 1A
    • C9orf32
    • Chromosome 9 open reading frame 32
    • Methyltransferase like 11A
    • Methyltransferase-like protein 11A
    • Mettl11a
    • N-terminal RCC1 methyltransferase
    • NRMT
    • NTM1A
    • NTM1A_HUMAN
    • NTMT1
    • X-Pro-Lys N-terminal protein methyltransferase 1A
    see all
  • Function

    Alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes mono-, di- or tri-methylation of exposed alpha-amino group of Ala, Pro or Ser residue in the [Ala/Pro/Ser]-Pro-Lys motif. Mediates the N-terminal methylation of KLHL31, MYL2, MYL3, RB1, RCC1, RPL23A and SET. Required during mitosis for normal bipolar spindle formation and chromosome segregation.
  • Sequence similarities

    Belongs to the methyltransferase superfamily. NTM1 family.
  • Cellular localization

    Nucleus. Predominantly nuclear.
  • Information by UniProt

Images

  • 15% SDS-PAGE analysis of ab211312 (3 μg).

References

ab211312 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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