Description

  • Product name

    Recombinant Human MGAT2 protein (denatured)
    See all MGAT2 proteins and peptides
  • Purity

    > 85 % SDS-PAGE.

  • Expression system

    Escherichia coli
  • Accession

  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MGSSHHHHHH SSGLVPRGSH MRQRKNEALA PPLLDAEPAR GAGGRGGDHP SVAVGIRRVS NVSAASLVPA VPQPEADNLT LRYRSLVYQL NFDQTLRNVD KAGTWAPREL VLVVQVHNRP EYLRLLLDSL RKAQGIDNVL VIFSHDFWST EINQLIAGVN FCPVLQVFFP FSIQLYPNEF PGSDPRDCPR DLPKNAALKL GCINAEYPDS FGHYREAKFS QTKHHWWWKL HFVWERVKIL RDYAGLILFL EEDHYLAPDF YHVFKKMWKL KQQECPECDV LSLGTYSASR SFYGMADKVD VKTWKSTEHN MGLALTRNAY QKLIECTDTF CTYDDYNWDW TLQYLTVSCL PKFWKVLVPQ IPRIFHAGDC GMHHKKTCRP STQSAQIESL LNNNKQYMFP ETLTISEKFT VVAISPPRKN GGWGDIRDHE LCKSYRRLQ
    • Predicted molecular weight

      50 kDa including tags
    • Amino acids

      30 to 447
    • Tags

      His tag N-Terminus
    • Additional sequence information

      Lumenal domain (NP_002399).
  • Description

    Recombinant Human MGAT2 protein

Specifications

Our Abpromise guarantee covers the use of ab177615 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 2.4% Urea, 0.32% Tris HCl, 10% Glycerol

General Info

  • Alternative names

    • Alpha 1,6 mannosyl glycoprotein 2 beta N acetylglucosaminyltransferase
    • Beta 1,2 N acetylglucosaminyltransferase II
    • CDG2A
    • CDGS2
    • GlcNAc T II
    • GLCNACTII
    • GNT II
    • GNT2
    • Mannoside acetylglucosaminyltransferase 2
    • N glycosyl oligosaccharide glycoprotein N acetylglucosaminyltransferase II
    • UDP N acetylglucosamine:alpha 6 D mannoside beta 1,2 N acetylglucosaminyltransferase II
    see all
  • Relevance

    MGAT2 is a Golgi enzyme catalyzing an essential step in the conversion of oligomannose to complex N-glycans. The enzyme has the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal-anchor domain, and a C-terminal catalytic domain. Mutations in its gene may lead to carbohydrate-deficient glycoprotein syndrome, type II. The product of this gene is a Golgi enzyme catalyzing an essential step in the conversion of oligomannose to complex N-glycans. The enzyme has the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal-anchor domain, and a C-terminal catalytic domain.
  • Cellular localization

    Golgi Apparatus membrane; type II membrane protein

Images

  • 15% SDS-PAGE analysis of ab177615 (3μg)

References

ab177615 has not yet been referenced specifically in any publications.

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