Product nameRecombinant Human MGMT protein
See all MGMT proteins and peptides
Protein lengthFull length protein
Amino Acid Sequence
SequenceMGSSHHHHHH SSGLVPRGSH MDKDCEMKRT TLDSPLGKLE LSGCEQGLHE IKLLGKGTSA ADAVEVPAPA AVLGGPEPLM QCTAWLNAYF HQPEAIEEFP VPAFHHPVFQ QESFTRQVLW KLLKVVKFGE VISYQQLAAL AGNPKAARAV GGAMRGNPVP ILIPCHRVVC SSGAVGNYSG GLAVKEWLLA HEGHRLGKPG LGGSSGLAGA WLKGAGATSG SPPAGRN
Our Abpromise guarantee covers the use of ab79251 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Purity> 95 % SDS-PAGE.
ab79251 is purified using conventional chromatography techniques. Endotoxin Level:< 1.0 EU per 1 µg of protein (determined by LAL method)
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Constituents: 0.0154% DTT, 0.316% Tris HCl, 10% Glycerol
- 6 O methylguanine DNA methyltransferase
- 6-O-methylguanine-DNA methyltransferase
FunctionInvolved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
Sequence similaritiesBelongs to the MGMT family.
- Information by UniProt
ab79251 has not yet been referenced specifically in any publications.