Description

  • Product name

    Recombinant Human MKK6 protein (denatured)
    See all MKK6 proteins and peptides
  • Purity

    > 85 % SDS-PAGE.
    Purified using conventional chromatography techniques.
  • Expression system

    Escherichia coli
  • Accession

  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MGSSHHHHHH SSGLVPRGSH MLEPIMELGR GAYGVVEKMR HVPSGQIMAV KRIRATVNSQ EQKRLLMDLD ISMRTVDCPF TVTFYGALFR EGDVWICMEL MDTSLDKFYK QVIDKGQTIP EDILGKIAVS IVKALEHLHS KLSVIHRDVK PSNVLINALG QVKMCDFGIS GYLVDEVAKE IDAGCKPYMA PERINPELNQ KGYSVKSDIW SLGITMIELA ILRFPYDSWG TPFQQLKQVV EEPSPQLPAD KFSAEFVDFT SQCLKKNSKE RPTYPELMQH PFF
    • Predicted molecular weight

      32 kDa including tags
    • Amino acids

      53 to 314
    • Tags

      His tag N-Terminus
    • Additional sequence information

      NP_002749.

Specifications

Our Abpromise guarantee covers the use of ab202240 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Liquid
  • Additional notes

     This product was previously labelled as MEK6

     

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8
    Constituents: 0.32% Tris HCl, 10% Glycerol

General Info

  • Alternative names

    • Dual specificity mitogen activated protein kinase kinase 6
    • Dual specificity mitogen-activated protein kinase kinase 6
    • MAP kinase kinase 6
    • MAP2K6
    • MAPK/ERK kinase 6
    • MAPKK 6
    • MAPKK6
    • MEK 6
    • MEK6
    • Mitogen Activated Protein Kinase Kinase 6
    • MKK 6
    • MKK6
    • MP2K6_HUMAN
    • PRKMK6
    • protein kinase
    • Protein kinase mitogen activated kinase 6
    • protein kinase, mitogen-activated, kinase 6 (MAP kinase kinase 6)
    • SAPK kinase 3
    • SAPKK-3
    • SAPKK3
    • SKK3
    • Stress-activated protein kinase kinase 3
    see all
  • Function

    Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in MAP kinase p38 exclusively.
  • Tissue specificity

    Isoform 2 is only expressed in skeletal muscle. Isoform 1 is expressed in skeletal muscle, heart, and in lesser extent in liver or pancreas.
  • Sequence similarities

    Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.
    Contains 1 protein kinase domain.
  • Post-translational
    modifications

    Weakly autophosphorylated.
    Acetylation of Ser-207 and Thr-211 by Yersinia yopJ prevents phosphorylation and activation, thus blocking the MAPK signaling pathway.
  • Information by UniProt

Images

  • 15% SDS-PAGE analysis of ab202240 (3µg).

References

ab202240 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab202240.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up