Recombinant Human MMP23 protein (ab160066)
Key features and details
- Expression system: Wheat germ
- Tags: GST tag N-Terminus
- Suitable for: ELISA, WB
Description
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Product name
Recombinant Human MMP23 protein
See all MMP23 proteins and peptides -
Expression system
Wheat germ -
Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
MGRGARVPSEAPGAGVERRWLGAALVALCLLPALVLLARLGAPAVPAWSA AQGDVAALGLSAVPPTRVPGPLAPRRRRYTLTPARLRWDHFNLTYRILSF PRNLLSPRETRRALAAAFRMWSDVSPFSFREVAPEQPSDLRIGFYPINHT DCLVSALHHCFDGPTGELAHAFFPPHGGIHFDDSEYWVLGPTRYSWKKGV WLTDLVHVAAHEIGHALGLMHSQHGRALMHLNATLRGWKALSQDELWGLH RLYGCLDRLFVCASWARRGFCDARRRLMKRLCPSSCDFCYEFPFPTVATT PPPPRTKTRLVPEGRNVTFRCGQKILHKKGKVYWYKDQEPLEFSYPGYLA LGEAHLSIIANAVNEGTYTCVVRRQQRVLTTYSWRVRVRG -
Amino acids
1 to 390 -
Tags
GST tag N-Terminus
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Specifications
Our Abpromise guarantee covers the use of ab160066 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
ELISA
Western blot
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Form
Liquid -
Additional notes
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
General Info
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Alternative names
- Femalysin
- Matrix metallopeptidase 21
- Matrix metallopeptidase 23A
see all -
Function
Protease. May regulate the surface expression of some potassum channels by retaining them in the endoplasmic reticulum. -
Tissue specificity
Predominantly expressed in ovary, testis and prostate. -
Sequence similarities
Belongs to the peptidase M10A family.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain. -
Domain
The toxin-like domain associates with, and blocks several potassium channels in the nanomolar to low micromolar range. The relative affinity is Kv1.6 > Kv1.3 > Kv1.1 = Kv3.2 > Kv1.4. -
Post-translational
modificationsN-glycosylated.
Proteolytic cleavage might yield an active form. -
Cellular localization
Endoplasmic reticulum membrane. Membrane. A secreted form produced by proteolytic cleavage may also exist. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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Datasheet download
References (0)
ab160066 has not yet been referenced specifically in any publications.