The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 mg/ml.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
homolog of yeast MMS19
MET18MMS19 nucleotide excision repair homolog (S. cerevisiae)
MMS19 nucleotide excision repair protein homolog
MMS19 nucleotide excision repair, S. cerevisiae, homolog of
MMS19-like (MET18 homolog, S. cerevisiae)
May play a role in nucleotide excision repair (NER) and RNA polymerase II (POL II) transcription by interacting with ERCC2/XPD and ERCC3/XPB helicases, both subunits of NER-transcription factor TFIIH. May also function as a transcriptional coactivator of estrogen receptor (ER). May be involved in regulation of ER activity by bridging TFIIH with ER or may facilitate TFIIH-mediated phosphorylation of ER in specific promoters and cell types. As part of the mitotic spindle-associated MMXD complex it plays a role in chromosome segregation.
Ubiquitously expressed with higher expression in testis.
Belongs to the MET18/MMS19 family. Contains 7 HEAT repeats.