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Recombinant Human MRGX protein (ab172166)

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SDS-PAGE - Recombinant Human MRGX protein (ab172166)

    Key features and details

    • Expression system: Escherichia coli
    • Purity: > 95% SDS-PAGE
    • Tags: His tag C-Terminus
    • Suitable for: SDS-PAGE, HPLC

    Description

    • Product name

      Recombinant Human MRGX protein
      See all MRGX proteins and peptides
    • Purity

      > 95 % SDS-PAGE.
      Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
    • Endotoxin level

      1.000 Eu/µg
    • Expression system

      Escherichia coli
    • Accession

      Q15014
    • Protein length

      Full length protein
    • Animal free

      No
    • Nature

      Recombinant
      • Species

        Human
      • Sequence

        MSSRKQGSQPRGQQSAEEENFKKPTRSNMQRSKMRGASSGKKTAGPQQKN LEPALPGRWGGRSAENPPSGSVRKTRKNKQKTPGNGDGGSTSEAPQPPRK KRARADPTVESEEAFKNRMEVKVKIPEELKPWLVEDWDLVTRQKQLFQLP AKKNVDAILEEYANCKKSQGNVDNKEYAVNEVVAGIKEYFNVMLGTQLLY KFERPQYAEILLAHPDAPMSQVYGAPHLLRLFVRIGAMLAYTPLDEKSLA LLLGYLHDFL KYLAKNSASLFTASDYKVASAEYHRKALLEHHHHHH
      • Predicted molecular weight

        33 kDa including tags
      • Amino acids

        1 to 288
      • Tags

        His tag C-Terminus

    Associated products

    • Related Products

      • Anti-6X His tag® antibody [HIS.H8] (ab18184)
      • Anti-6X His tag® antibody [4D11] (ab5000)
      • Anti-6X His tag® antibody (ab9108)

    Specifications

    Our Abpromise guarantee covers the use of ab172166 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

      HPLC

    • Form

      Lyophilized
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Store at -20°C. Avoid freeze / thaw cycle.

      pH: 7.40
      Constituents: 99% PBS, 0.88% Sodium chloride

    General Info

    • Alternative names

      • KIAA0026
      • MO4L2_HUMAN
      • MORF related gene X protein
      • MORF-related gene X protein
      • Morf4l2
      • MORFL2
      • Mortality Factor 4 like 2
      • Mortality factor 4 like protein 2
      • Mortality factor 4-like protein 2
      • MRGX
      • MSL3 2 protein
      • Protein MSL3-2
      • Transcription factor like protein MRGX
      • Transcription factor-like protein MRGX
      see all
    • Function

      Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones.
    • Sequence similarities

      Belongs to the MRG family.
    • Cellular localization

      Nucleus.
    • Target information above from: UniProt accession Q15014 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt

    Images

    • SDS-PAGE - Recombinant Human MRGX protein (ab172166)
      SDS-PAGE - Recombinant Human MRGX protein (ab172166)

      SDS-PAGE gel of ab172166 under non reduced (lane 1) and reduced (lane 2) conditions.

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab172166? Please let us know so that we can cite the reference in this datasheet.

    ab172166 has not yet been referenced specifically in any publications.

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