Description

  • Product name

    Recombinant Human MT3 protein (Tagged)
    See all MT3 proteins and peptides
  • Purity

    > 90 % SDS-PAGE.

  • Expression system

    Escherichia coli
  • Accession

  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MDPETCPCPSGGSCTCADSCKCEGCKCTSCKKSCCSCCPAECEKCAKDCV CKGGEAAEAEAEKCSCCQ
    • Predicted molecular weight

      23 kDa including tags
    • Amino acids

      1 to 68
    • Tags

      His tag N-Terminus
    • Additional sequence information

      N-terminal 6xHis-SUMO-tag.

Specifications

Our Abpromise guarantee covers the use of ab235794 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Constituents: Tris buffer, 50% Glycerol

General Info

  • Alternative names

    • GIF
    • GIFB
    • GRIF
    • Growth inhibitory factor
    • Metallothionein 3
    • Metallothionein 3 (growth inhibitory factor (neurotrophic))
    • Metallothionein III
    • Metallothionein-3
    • Metallothionein-III
    • Mt 3
    • MT III
    • MT-3
    • MT-III
    • MT3
    • MT3_HUMAN
    • ZnMT3
    see all
  • Function

    Binds heavy metals. Contains three zinc and three copper atoms per polypeptide chain and only a negligible amount of cadmium. Inhibits survival and neurite formation of cortical neurons in vitro.
  • Tissue specificity

    Abundant in a subset of astrocytes in the normal human brain, but greatly reduced in the Alzheimer disease (AD) brain.
  • Sequence similarities

    Belongs to the metallothionein superfamily. Type 1 family.
  • Information by UniProt

Images

  • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) analysis with 5% enrichment gel and 15% separation gel of ab235794.

References

ab235794 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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