The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 mg/ml.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
Angiotensin II type 2 receptor interacting protein
AT2 receptor interacting protein
AT2 receptor-binding protein
AT2R binding protein
Erythroid differentiation related
Microtubule associated tumor suppressor 1
Mitochondrial tumor suppressor 1
Mitochondrial tumor suppressor gene 1
Transcription factor MTSG1
Multiple alternatively spliced transcript variants encoding different isoforms have been found for the MTUS1 (Mitochondrial tumor suppressor 1) gene. One of the transcript variants has been shown to encode a mitochondrial protein that acts as a tumor suppressor and cooperates with the angiotension II (AT2) receptor (AGTR2) to inhibit ERK2 activation and cell proliferation. MTUS1 polypeptides are identical in their carboxy-terminal region carrying four coiled-coil domains. In their amino-terminal portion, MTUS1 polypeptides exhibit distinct motifs for localisation in the cytosol, nucleus or cell membrane, suggesting that MTUS1 gene products may be involved in a variety of intracellular functions in an AT2-dependent and independent manner.
Cell Membrane, Golgi Apparatus, Mitochondrial and Nuclear. Note=In neurons, translocates into the nucleus after treatment with angiotensin-II.
SDS-PAGE - Recombinant Human MTUS1 protein (ab163572)
ab163572 on a 12.5% SDS-PAGE stained with Coomassie Blue.
has not yet been referenced specifically in any publications.
Publishing research using ab163572? Please let us know so that we can cite the reference in this datasheet.
Customer reviews and Q&As
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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