Recombinant Human MUC20 protein (ab165875)
- Datasheet
- References
- Protocols
Overview
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Product nameRecombinant Human MUC20 protein
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Protein lengthFull length protein
Description
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NatureRecombinant
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SourceWheat germ
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Amino Acid Sequence
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SpeciesHuman
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SequenceMGCLWGLALPLFFFCWEVGVSGSSAGPSTRRADTAMTTDDTEVPAMTLAP GHAALETQTLSAETSSRASTPAGPIPEAETRGAKRISPARETRSFTKTSP NFMVLIATSVETSAASGSPEGAGMTTVQTITGSDPEEAIFDTLCTDDSSE EAKTLTMDILTLAHTSTEAKGLSSESSASSDGPHPVITPSRASESSASSD GPHPVITPSRASESSASSDGPHPVITPSWSPGSDVTLLAEALVTVTNIEV INCSITEIETTTSSIPGASDIDLIPTEGVKASSTSDPPALPDSTEAKPHI TEVTASAETLSTAGTTESAAPHATVGTPLPTNSATEREVTAPGATTLSGA LVTVSRNPLEETSALSVETPSYVKVSGAAPVSIEAGSAVGKTTSFAGSSA SSYSPSEAALKNFTPSETPTMDIATKGPFPTSRDPLPSVPPTTTNSSRGT NSTLAKITTSAKTTMKPPTATPTTARTRPTTDVSAGENGGFLLLRLSVAS PEDLTDPRVAERLMQQLHRELHAHAPHFQVSLLRVRRG
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Amino acids1 to 538
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Tagsproprietary tag N-Terminus
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Specifications
Our Abpromise guarantee covers the use of ab165875 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
Western blot
ELISA
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FormLiquid
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Additional notesProtein concentration is above or equal to 0.05 mg/ml.
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
General Info
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Alternative names
- MUC 20
- MUC-20
- Muc20
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FunctionMay regulate MET signaling cascade. Seems to decrease hepatocyte growth factor (HGF)-induced transient MAPK activation. Blocks GRB2 recruitment to MET thus suppressing the GRB2-RAS pathway. Inhibits HGF-induced proliferation of MMP1 and MMP9 expression.
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Tissue specificityHighly expressed in kidney, moderately in placenta, lung, prostate, liver, and digestive system. In the kidney, localized in the proximal tubules but not in the glomerulus or distal tubules. Detected in most of the male urogenital tract epithelia, with the exception of epididymis.
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Cellular localizationSecreted. Apical cell membrane. Basolateral cell membrane. Cell projection > microvillus membrane.
- Information by UniProt
Images
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SDS-PAGE - Recombinant Human MUC20 protein (ab165875)ab165875 on a 12.5% SDS-PAGE stained with Coomassie Blue.
Datasheets and documents
References
ab165875 has not yet been referenced specifically in any publications.
