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Full length protein
Amino Acid Sequence
MAPPVAERGLKSVVWQKIKATVFDDCKKEGEWKIMLLDEFTTKLLASCCK MTDLLEEGITVVENIYKNREPVRQMKALYFITPTSKSVDCFLHDFASKSE NKYRAAYIYFTDFCPDNLFNKIKASCSKSIRRCKEINISFIPHESQVYTR DVPDAFYYCYSPDPGNAKGKDAIMETMADQIVTVCATLDENPGVRYKSKP LDNASKLAQLVEKKLEDYYKIDEKSLIKGKTHSQLLIIDRGFDPVSTVLH ELTFQAMAYDLLPIENDTYKYKTDGKEKEAILEEEDDLWVRIRHRHIAVV LEEIPKLMKEISSTKKATEGKTSLSALTQLMKKMPHFRKQITKQVVHLNL AEDCMNKFKLNIEKLCKTEQDLALGTDAEGQKVKDSMRVLLPVLLNKNHD NCDKIRAILLYIFSINGTTEENLDRLIQNVKIENESDMIRNWSYLGVPIV PQSQQGKPLRKDRSAEETFQLSRWTPFIKDIMEDAIDNRLDSKEWPYCSQ CPAVWNGSGAVSARQKPRANYLEDRKNGSKLIVFVIGGITYSEVRCAYEV SQAHKSCEVIIGSTHVLTPKKLLDDIKMLNKPKDKVSLIKDE
1 to 592
proprietary tag N-Terminus
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituents: 0.31% Glutathione, 0.79% Tris HCl
- Munc18 3
- Munc18 c
- Platelet Sec1 protein
Together with STX4 and VAMP2, may play a role in insulin-dependent movement of GLUT4 and in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes.
Megakaryocytes and platelets.
Belongs to the STXBP/unc-18/SEC1 family.
Phosphorylated by PKC in platelets in response to thrombin stimulation; phosphorylation inhibits binding to STX4.
Cytoplasm > cytosol. Cell membrane. In platelets, predominantly cytosolic. Low amounts membrane-associated.
Information by UniProt
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"