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    recombinant-human-narg1-protein-ab164208.pdf

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Epigenetics and Nuclear Signaling Chromatin Modifying Enzymes Acetylation HAT
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Recombinant Human NARG1 protein (ab164208)

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SDS-PAGE - Recombinant Human NARG1 protein (ab164208)

    Key features and details

    • Expression system: Wheat germ
    • Tags: GST tag N-Terminus
    • Suitable for: ELISA, WB

    Description

    • Product name

      Recombinant Human NARG1 protein
    • Expression system

      Wheat germ
    • Protein length

      Protein fragment
    • Animal free

      No
    • Nature

      Recombinant
      • Species

        Human
      • Sequence

        HRLSAAKMVYYLDPSSQKRAIELATTLDESLTNRNLQTCMEVLEALYDGS LGDCKEAAEIYRANCHKLFPYALAFMPPGYEEDMKITVNGDSSAEAEEL
      • Amino acids

        764 to 862
      • Tags

        GST tag N-Terminus

    Specifications

    Our Abpromise guarantee covers the use of ab164208 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      ELISA

      Western blot

    • Form

      Liquid
    • Additional notes

       

       

    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

      pH: 8.00
      Constituents: 0.31% Glutathione, 0.79% Tris HCl

    General Info

    • Alternative names

      • 5730450D16Rik
      • 6330400I15
      • ASTBDN
      • GA19
      • Gastric cancer antigen Ga19
      • MGC29428
      • mNAT1
      • N alpha acetyltransferase 15, NatA auxiliary subunit
      • N terminal acetyltransferase
      • N(alpha) acetyltransferase 15, NatA auxiliary subunit
      • N-alpha-acetyltransferase 15
      • N-terminal acetyltransferase
      • Naa15
      • NAA15_HUMAN
      • NatA auxiliary subunit
      • NATH
      • NMDA receptor regulated 1
      • NMDA receptor regulated protein 1
      • NMDA receptor-regulated protein 1
      • Protein tubedown 1
      • Protein tubedown-1
      • Tbdn 1
      • Tbdn100
      • Transcriptional coactivator tubedown 100
      • tubedown-1
      see all
    • Function

      The NAA10-NAA15 complex displays alpha (N-terminal) acetyltransferase activity that may be important for vascular, hematopoietic and neuronal growth and development. Required to control retinal neovascularization in adult ocular endothelial cells. In complex with XRCC6 and XRCC5 (Ku80), up-regulates transcription from the osteocalcin promoter.
    • Tissue specificity

      Expressed at high levels in testis and in ocular endothelial cells. Also found in brain (corpus callosum), heart, colon, bone marrow and at lower levels in most adult tissues, including thyroid, liver, pancreas, mammary and salivary glands, lung, ovary, urogenital system and upper gastrointestinal tract. Overexpressed in gastric cancer, in papillary thyroid carcinomas and in a Burkitt lymphoma cell line (Daudi). Specifically suppressed in abnormal proliferating blood vessels in eyes of patients with proliferative diabetic retinopathy.
    • Sequence similarities

      Contains 8 TPR repeats.
    • Post-translational
      modifications

      Cleaved by caspases during apoptosis, resulting in a stable 35 kDa fragment.
    • Cellular localization

      Cytoplasm. Nucleus. Mainly cytoplasmic, nuclear in some cases. Present in the free cytosolic and cytoskeleton-bound polysomes, but not in the membrane-bound polysomes.
    • Target information above from: UniProt accession Q9BXJ9 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt

    Images

    • SDS-PAGE - Recombinant Human NARG1 protein (ab164208)
      SDS-PAGE - Recombinant Human NARG1 protein (ab164208)
      ab164208 on a 12.5% SDS-PAGE stained with Coomassie Blue.

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    Datasheets and documents

    • SDS download

    • Datasheet download

      Download

    References (0)

    Publishing research using ab164208? Please let us know so that we can cite the reference in this datasheet.

    ab164208 has not yet been referenced specifically in any publications.

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