Overview

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      TRYVDIALRTDMSDITKSYLSECGSCFWVGESEEKVVGTVGALPVDDPTL REKRLQLFHLSVDNEHRGQGIAKALVRTVLQFARDQGYSEVVLDTSN
    • Amino acids
      83 to 179
    • Tags
      proprietary tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab162568 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • Acetyltransferase 1
    • ATase1
    • Camello like protein 2
    • Camello-like protein 2
    • CML2
    • Hcml2
    • N acetyltransferase 8B
    • N acetyltransferase Camello 2
    • NAT8B
    • NAT8B_HUMAN
    • NAT8BP
    • Probable N acetyltransferase 8B
    • Putative N-acetyltransferase 8B
    see all
  • Function
    May have a lysine N-acetyltransferase activity catalyzing peptidyl-lysine N6-acetylation of various proteins. Thereby, may regulate apoptosis through the acetylation and the regulation of the expression of PROM1 (PubMed:24556617). May also regulate amyloid beta-peptide secretion through acetylation of BACE1 and the regulation of its expression in neurons (PubMed:19011241).
  • Sequence similarities
    Belongs to the camello family.
    Contains 1 N-acetyltransferase domain.
  • Cellular localization
    Endoplasmic reticulum-Golgi intermediate compartment membrane. Endoplasmic reticulum membrane. Enriched in the Endoplasmic reticulum-Golgi intermediate compartment.
  • Information by UniProt

Images

  • ab162568 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab162568 has not yet been referenced specifically in any publications.

Publishing research using ab162568? Please let us know so that we can cite the reference in this datasheet.

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