Recombinant Human Natriuretic Peptide Receptor A/GC-A protein (ab201407)

Description

  • Product name

    Recombinant Human Natriuretic Peptide Receptor A/GC-A protein
    See all Natriuretic Peptide Receptor A/GC-A proteins and peptides
  • Purity

    > 75 % SDS-PAGE.

  • Expression system

    Baculovirus infected Sf9 cells
  • Accession

  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      RKMQLE KELASELWRV RWEDVEPSSL ERHLRSAGSR LTLSGRGSNY GSLLTTEGQF QVFAKTAYYK GNLVAVKRVN RKRIELTRKV LFELKHMRDV QNEHLTRFVG ACTDPPNICI LTEYCPRGSL QDILENESIT LDWMFRYSLT NDIVKGMLFL HNGAICSHGN LKSSNCVVDG RFVLKITDYG LESFRDLDPE QGHTVYAKKL WTAPELLRMA SPPVRGSQAG DVYSFGIILQ EIALRSGVFH VEGLDLSPKE IIERVTRGEQ PPFRPSLALQ SHLEELGLLM QRCWAEDPQE RPPFQQIRLT LRKFNRENSS NILDNLLSRM EQYANNLEEL VEERTQAYLE EKRKAEALLY QILPHSVAEQ LKRGETVQAE AFDSVTIYFS DIVGFTALSA ESTPMQVVTL LNDLYTCFDA VIDNFDVYKV ETIGDAYMVV SGLPVRNGRL HACEVARMAL ALLDAVRSFR IRHRPQEQLR LRIGIHTGPV CAGVVGLKMP RYCLFGDTVN TASRMESNGE ALKIHLSSET KAVLEEFGGF ELELRGDVEM KGKGKVRTYW LLGERGSSTR G
    • Predicted molecular weight

      88 kDa including tags
    • Amino acids

      495 to 1061
    • Tags

      GST tag N-Terminus
    • Additional sequence information

      (BC063304)

Specifications

Our Abpromise guarantee covers the use of ab201407 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Liquid
  • Additional notes

    Previously labelled as Natriuretic Peptide Receptor A. 

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on Dry Ice. Store at -80°C. Avoid freeze / thaw cycle.

    pH: 7.50
    Constituents: 0.79% Tris HCl, 0.29% Sodium chloride, 0.31% Glutathione, 0.003% EDTA, 0.004% DTT, 0.002% PMSF, 25% Glycerol

General Info

  • Alternative names

    • ANP-A
    • ANPa
    • ANPR-A
    • ANPRA
    • ANPRA_HUMAN
    • Atrial natriuretic peptide A type receptor
    • Atrial natriuretic peptide receptor 1
    • Atrial natriuretic peptide receptor A
    • Atrial natriuretic peptide receptor type A
    • Atrionatriuretic peptide receptor A
    • GC A
    • GC-A
    • Guanylate cyclase
    • Guanylate cyclase A
    • GUC2A
    • GUCY2A
    • Natriuretic peptide A type receptor
    • Natriuretic Peptide Receptor A
    • Natriuretic peptide receptor A/guanylate cyclase A
    • NPR-A
    • NPR1
    • NPRA
    see all
  • Function

    Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Has guanylate cyclase activity upon binding of the ligand.
  • Sequence similarities

    Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
    Contains 1 guanylate cyclase domain.
    Contains 1 protein kinase domain.
  • Post-translational
    modifications

    Phosphorylation of the protein kinase-like domain is required for full activation by ANP.
  • Cellular localization

    Membrane.
  • Information by UniProt

Images

  • SDS PAGE analysis of ab201407

References

ab201407 has not yet been referenced specifically in any publications.

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