Recombinant Human Natriuretic peptides A protein (ab114317)

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SDS-PAGE - Recombinant Human Natriuretic peptides A protein (ab114317)

    Key features and details

    • Expression system: Wheat germ
    • Suitable for: SDS-PAGE, ELISA, WB

    Description

    • Product name

      Recombinant Human Natriuretic peptides A protein

    • Expression system

      Wheat germ

    • Accession

      P01160

    • Protein length

      Full length protein

    • Animal free

      No

    • Nature

      Recombinant

      • Species

        Human

      • Sequence

        MSSFSTTTVSFLLLLAFQLLGQTRANPMYNAVSNADLMDFKNLLDHLEEK MPLEDEVVPPQVLSEPNEEAGAALSPLPEVPPWTGEVSPAQRDGGALGRG PWDSSDRSALLKSKLRALLTAPRSLRRSSCFGGRMDGIGAQSGLGCNSFR YRR

      • Predicted molecular weight

        43 kDa including tags

      • Amino acids

        1 to 153

    Specifications

    Our Abpromise guarantee covers the use of ab114317 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

      ELISA

      Western blot

    • Form

      Liquid
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

      pH: 8.00
      Constituents: 0.3% Glutathione, 0.79% Tris HCl

    General Info

    • Alternative names

      • ANF
      • ANF_HUMAN
      • ANP
      • ATFB6
      • Atrial natriuretic factor
      • Atrial natriuretic peptide
      • Atriopeptin
      • Cardiodilatin
      • Cardiodilatin related peptide
      • Cardiodilatin-related peptide
      • Cardionatrin
      • CDD
      • CDD ANF
      • CDD-ANF
      • CDP
      • Natriuretic peptide A
      • Natriuretic peptide precursor A
      • NPPA
      • PND
      • Prepronatriodilatin
      see all

    • Function

      Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.

    • Involvement in disease

      Atrial standstill 2
      Atrial fibrillation, familial, 6

    • Sequence similarities

      Belongs to the natriuretic peptide family.

    • Post-translational
      modifications

      Cleaved by CORIN upon secretion to produce the functional hormone.
      Atrial natriuretic factor: Cleaved by MME. The cleavage initiates degradation of the factor and thereby regulate its activity.

    • Cellular localization

      Secreted.
    • Information by UniProt

    Images

    • SDS-PAGE - Recombinant Human Natriuretic peptides A protein (ab114317)
      SDS-PAGE - Recombinant Human Natriuretic peptides A protein (ab114317)
      SDS-PAGE analysis of ab114317 on a 12.5% gel stained with Coomassie Blue.

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab114317? Please let us know so that we can cite the reference in this datasheet.

    ab114317 has not yet been referenced specifically in any publications.

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