Product nameRecombinant Human Natriuretic peptides A protein
Protein lengthFull length protein
Amino Acid Sequence
SequenceMSSFSTTTVSFLLLLAFQLLGQTRANPMYNAVSNADLMDFKNLLDHLEEK MPLEDEVVPPQVLSEPNEEAGAALSPLPEVPPWTGEVSPAQRDGGALGRG PWDSSDRSALLKSKLRALLTAPRSLRRSSCFGGRMDGIGAQSGLGCNSFR YRR
Molecular weight43 kDa including tags
Amino acids1 to 153
- Anti-proANP antibody (ab14160)
- Anti-proANP antibody (ab14349)
- Anti-Natriuretic peptides A antibody [L11-11-D6-B4] (ab14442)
- Anti-proANP antibody (ab14443)
- Anti-Natriuretic peptides A antibody (Biotin) (ab47847)
- Anti-Natriuretic peptides A antibody (ab76743)
- Anti-proANP antibody (ab85306)
- Anti-proANP antibody (ab91250)
Our Abpromise guarantee covers the use of ab114317 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Additional notesProtein concentration is above or equal to 0.05 mg/ml.
Best used within three months from the date of receipt.
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituents: 0.3% Glutathione, 0.79% Tris HCl
FunctionHormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.
Involvement in diseaseAtrial standstill 2
Atrial fibrillation, familial, 6
Sequence similaritiesBelongs to the natriuretic peptide family.
modificationsCleaved by CORIN upon secretion to produce the functional hormone.
Atrial natriuretic factor: Cleaved by MME. The cleavage initiates degradation of the factor and thereby regulate its activity.
- Information by UniProt
ab114317 has not yet been referenced specifically in any publications.