Description

  • Product name

    Recombinant Human Nck-2 protein
  • Purity

    > 85 % SDS-PAGE.
    ab167862 is purified using conventional chromatography techniques.
  • Expression system

    Escherichia coli
  • Accession

  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MGSSHHHHHH SSGLVPRGSH MGSMTEEVIV IAKWDYTAQQ DQELDIKKNE RLWLLDDSKT WWRVRNAANR TGYVPSNYVE RKNSLKKGSL VKNLKDTLGL GKTRRKTSAR DASPTPSTDA EYPANGSGAD RIYDLNIPAF VKFAYVAERE DELSLVKGSR VTVMEKCSDG WWRGSYNGQI GWFPSNYVLE EVDEAAAESP SFLSLRKGAS LSNGQGSRVL HVVQTLYPFS SVTEEELNFE KGETMEVIEK PENDPEWWKC KNARGQVGLV PKNYVVVLSD GPALHPAHAP QISYTGPSSS GRFAGREWYY GNVTRHQAEC ALNERGVEGD FLIRDSESSP SDFSVSLKAS GKNKHFKVQL VDNVYCIGQR RFHTMDELVE HYKKAPIFTS EHGEKLYLVR ALQ
    • Predicted molecular weight

      45 kDa including tags
    • Amino acids

      1 to 380
    • Tags

      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab167862 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry

    MALDI-TOF
  • Form

    Liquid
  • Additional notes

    Protein previously labeled as Nck beta.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris-HCl buffer, 0.02% DTT, 30% Glycerol, 0.88% Sodium chloride

General Info

  • Alternative names

    • Cytoplasmic protein NCK2
    • GRB4
    • Growth factor receptor bound protein 4
    • NCK adaptor protein 2
    • Nck-2
    • NCK2
    • NCK2_HUMAN
    • NCKbeta
    • Non-catalytic region of tyrosine kinase adaptor protein 2
    • Noncatalytic region of tyrosine kinase beta
    • SH2/SH3 adaptor protein NCK-beta
    see all
  • Function

    Adapter protein which associates with tyrosine-phosphorylated growth factor receptors or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1.
  • Tissue specificity

    Ubiquitous.
  • Sequence similarities

    Contains 1 SH2 domain.
    Contains 3 SH3 domains.
  • Cellular localization

    Cytoplasm. Endoplasmic reticulum.
  • Information by UniProt

Images

  • 15% SDS-PAGE analysis of ab167862 (3µg)

References

ab167862 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab167862.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up