Recombinant Human NDRG2 protein (denatured) (ab131671)

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SDS-PAGE - Recombinant Human NDRG2 protein (denatured) (ab131671)

    Key features and details

    • Expression system: Escherichia coli
    • Purity: > 90% SDS-PAGE
    • Tags: His tag N-Terminus
    • Suitable for: SDS-PAGE

    Description

    • Product name

      Recombinant Human NDRG2 protein (denatured)

    • Purity

      > 90 % SDS-PAGE.

    • Expression system

      Escherichia coli

    • Accession

      Q9UN36

    • Protein length

      Full length protein

    • Animal free

      No

    • Nature

      Recombinant

      • Species

        Human

      • Sequence

        MGSSHHHHHH SSGLVPRGSH MGSHMAELQE VQITEEKPLL PGQTPEAAKT HSVETPYGSV TFTVYGTPKP KRPAILTYHD VGLNYKSCFQ PLFQFEDMQE IIQNFVRVHV DAPGMEEGAP VFPLGYQYPS LDQLADMIPC VLQYLNFSTI IGVGVGAGAY ILARYALNHP DTVEGLVLIN IDPNAKGWMD WAAHKLTGLT SSIPEMILGH LFSQEELSGN SELIQKYRNI ITHAPNLDNI ELYWNSYNNR RDLNFERGGD ITLRCPVMLV VGDQAPHEDA VVECNSKLDP TQTSFLKMAD SGGQPQLTQP GKLTEAFKYF LQGMGYMASS CMTRLSRSRT ASLTSAASVD GNRSRSRTLS QSSESGTLSS GPPGHTMEVS C

      • Predicted molecular weight

        42 kDa including tags

      • Amino acids

        1 to 357

      • Tags

        His tag N-Terminus

    Specifications

    Our Abpromise guarantee covers the use of ab131671 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

    • Form

      Liquid
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      pH: 8.00
      Constituents: 2.4% Urea, 0.32% Tris HCl, 10% Glycerol (glycerin, glycerine), 0.58% Sodium chloride

    General Info

    • Alternative names

      • Antidepressant related protein ADRG123
      • Cytoplasmic protein Ndr1
      • DKFZp781G1938
      • FLJ25522
      • KIAA1248
      • N myc downstream regulated gene 2
      • N myc downstream regulator 2
      • NDR1 related protein NDR2
      • NDRG 2
      • NDRG family member 2
      • NDRG1 related protein
      • NDRG2
      • NDRG2_HUMAN
      • Protein NDRG2
      • Protein Syld709613
      • SYLD
      • Syld709613 protein
      see all

    • Function

      May be involved in dendritic cell and neuron differentiation. May have anti-tumor activity.

    • Tissue specificity

      Highly expressed in brain, heart, skeletal muscle and salivary gland, and moderately in kidney and liver. Expressed in dendritic cells, but not in other blood cells. Expression levels are low in pancreatic and liver cancer tissues; absent in meningioma. Expressed in low-grade gliomas but present at low levels in glioblastoma. Isoform 1 and isoform 2 are present in brain neurons and up-regulated in Alzheimer disease (at protein level).

    • Sequence similarities

      Belongs to the NDRG family.

    • Developmental stage

      Specifically expressed during dendritic cell differentiation (in vitro). Expression is low in fetal brain and increases during brain postnatal development.

    • Cellular localization

      Cytoplasm. Cytoplasm > perinuclear region. Perinuclear in neurons.
    • Information by UniProt

    Images

    • SDS-PAGE - Recombinant Human NDRG2 protein (denatured) (ab131671)
      SDS-PAGE - Recombinant Human NDRG2 protein (denatured) (ab131671)
      15% SDS-PAGE showing ab131671 at approximately 41.8 kDa (3µg).

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab131671? Please let us know so that we can cite the reference in this datasheet.

    ab131671 has not yet been referenced specifically in any publications.

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