Overview

Description

  • Nature

    Recombinant
  • Source

    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species

      Human
    • Sequence

      MGSSHHHHHH SSGLVPRGSH MGSHMAELQE VQITEEKPLL PGQTPEAAKT HSVETPYGSV TFTVYGTPKP KRPAILTYHD VGLNYKSCFQ PLFQFEDMQE IIQNFVRVHV DAPGMEEGAP VFPLGYQYPS LDQLADMIPC VLQYLNFSTI IGVGVGAGAY ILARYALNHP DTVEGLVLIN IDPNAKGWMD WAAHKLTGLT SSIPEMILGH LFSQEELSGN SELIQKYRNI ITHAPNLDNI ELYWNSYNNR RDLNFERGGD ITLRCPVMLV VGDQAPHEDA VVECNSKLDP TQTSFLKMAD SGGQPQLTQP GKLTEAFKYF LQGMGYMASS CMTRLSRSRT ASLTSAASVD GNRSRSRTLS QSSESGTLSS GPPGHTMEVS C
    • Molecular weight

      42 kDa including tags
    • Amino acids

      1 to 357
    • Tags

      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab131671 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity

    > 90 % SDS-PAGE.

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 2.4% Urea, 0.32% Tris HCl, 10% Glycerol, 0.58% Sodium chloride

General Info

  • Alternative names

    • Antidepressant related protein ADRG123
    • Cytoplasmic protein Ndr1
    • DKFZp781G1938
    • FLJ25522
    • KIAA1248
    • N myc downstream regulated gene 2
    • N myc downstream regulator 2
    • NDR1 related protein NDR2
    • NDRG 2
    • NDRG family member 2
    • NDRG1 related protein
    • NDRG2
    • NDRG2_HUMAN
    • Protein NDRG2
    • Protein Syld709613
    • SYLD
    • Syld709613 protein
    see all
  • Function

    May be involved in dendritic cell and neuron differentiation. May have anti-tumor activity.
  • Tissue specificity

    Highly expressed in brain, heart, skeletal muscle and salivary gland, and moderately in kidney and liver. Expressed in dendritic cells, but not in other blood cells. Expression levels are low in pancreatic and liver cancer tissues; absent in meningioma. Expressed in low-grade gliomas but present at low levels in glioblastoma. Isoform 1 and isoform 2 are present in brain neurons and up-regulated in Alzheimer disease (at protein level).
  • Sequence similarities

    Belongs to the NDRG family.
  • Developmental stage

    Specifically expressed during dendritic cell differentiation (in vitro). Expression is low in fetal brain and increases during brain postnatal development.
  • Cellular localization

    Cytoplasm. Cytoplasm > perinuclear region. Perinuclear in neurons.
  • Information by UniProt

Images

  • 15% SDS-PAGE showing ab131671 at approximately 41.8 kDa (3µg).

References

ab131671 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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