Recombinant Human NDRG2 protein (denatured) (ab131671)
- Datasheet
- References
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Overview
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Product name
Recombinant Human NDRG2 protein (denatured)
See all NDRG2 proteins and peptides -
Protein length
Full length protein
Description
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Nature
Recombinant -
Source
Escherichia coli -
Amino Acid Sequence
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Accession
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Species
Human -
Sequence
MGSSHHHHHH SSGLVPRGSH MGSHMAELQE VQITEEKPLL PGQTPEAAKT HSVETPYGSV TFTVYGTPKP KRPAILTYHD VGLNYKSCFQ PLFQFEDMQE IIQNFVRVHV DAPGMEEGAP VFPLGYQYPS LDQLADMIPC VLQYLNFSTI IGVGVGAGAY ILARYALNHP DTVEGLVLIN IDPNAKGWMD WAAHKLTGLT SSIPEMILGH LFSQEELSGN SELIQKYRNI ITHAPNLDNI ELYWNSYNNR RDLNFERGGD ITLRCPVMLV VGDQAPHEDA VVECNSKLDP TQTSFLKMAD SGGQPQLTQP GKLTEAFKYF LQGMGYMASS CMTRLSRSRT ASLTSAASVD GNRSRSRTLS QSSESGTLSS GPPGHTMEVS C -
Molecular weight
42 kDa including tags -
Amino acids
1 to 357 -
Tags
His tag N-Terminus
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Associated products
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Related Products
Specifications
Our Abpromise guarantee covers the use of ab131671 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
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Purity
> 90 % SDS-PAGE. -
Form
Liquid -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 8.00
Constituents: 2.4% Urea, 0.32% Tris HCl, 10% Glycerol, 0.58% Sodium chloride
General Info
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Alternative names
- Antidepressant related protein ADRG123
- Cytoplasmic protein Ndr1
- DKFZp781G1938
see all -
Function
May be involved in dendritic cell and neuron differentiation. May have anti-tumor activity. -
Tissue specificity
Highly expressed in brain, heart, skeletal muscle and salivary gland, and moderately in kidney and liver. Expressed in dendritic cells, but not in other blood cells. Expression levels are low in pancreatic and liver cancer tissues; absent in meningioma. Expressed in low-grade gliomas but present at low levels in glioblastoma. Isoform 1 and isoform 2 are present in brain neurons and up-regulated in Alzheimer disease (at protein level). -
Sequence similarities
Belongs to the NDRG family. -
Developmental stage
Specifically expressed during dendritic cell differentiation (in vitro). Expression is low in fetal brain and increases during brain postnatal development. -
Cellular localization
Cytoplasm. Cytoplasm > perinuclear region. Perinuclear in neurons. - Information by UniProt
Images
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SDS-PAGE - Recombinant Human NDRG2 protein (denatured) (ab131671)15% SDS-PAGE showing ab131671 at approximately 41.8 kDa (3µg).
Datasheets and documents
References
ab131671 has not yet been referenced specifically in any publications.
