Recombinant Human NDUFA1 protein (ab158959)
- Datasheet
- References
- Protocols
Overview
-
Product nameRecombinant Human NDUFA1 protein
See all NDUFA1 proteins and peptides -
Protein lengthFull length protein
Description
-
NatureRecombinant
-
SourceWheat germ
-
Amino Acid Sequence
-
SpeciesHuman
-
SequenceAYIHRFTNGGKEKRVAHFGYHWSLMERDRRISGVDRYYVSKGLENID
-
Amino acids24 to 70
-
Tagsproprietary tag N-Terminus
-
Specifications
Our Abpromise guarantee covers the use of ab158959 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
-
Applications
ELISA
Western blot
-
FormLiquid
-
Additional notesProtein concentration is above or equal to 0.05 mg/ml.
-
Concentration information loading...
Preparation and Storage
-
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
General Info
-
Alternative names
- CI MWFE
- CI-MWFE
- Complex I MWFE
see all -
FunctionAccessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
-
Tissue specificityPrimarily expressed in heart and skeletal muscle.
-
Involvement in diseaseDefects in NDUFA1 are a cause of mitochondrial complex I deficiency (MT-C1D) [MIM:252010]. A disorder of the mitochondrial respiratory chain that causes a wide range of clinical disorders, from lethal neonatal disease to adult-onset neurodegenerative disorders. Phenotypes include macrocephaly with progressive leukodystrophy, non-specific encephalopathy, cardiomyopathy, myopathy, liver disease, Leigh syndrome, Leber hereditary optic neuropathy, and some forms of Parkinson disease.
-
Sequence similaritiesBelongs to the complex I NDUFA1 subunit family.
-
Cellular localizationMitochondrion inner membrane.
- Information by UniProt
Images
-
SDS-PAGE - Recombinant Human NDUFA1 protein (ab158959)ab158959 on a 12.5% SDS-PAGE stained with Coomassie Blue.
Datasheets and documents
References
ab158959 has not yet been referenced specifically in any publications.
