The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 mg/ml.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
Guanine nucleotide regulatory protein oncogene
Neuroepithelial cell transforming gene 1
Neuroepithelial cell-transforming gene 1 protein
p65 Net1 proto oncogene
Proto-oncogene p65 Net1
Rho guanine nucleotide exchange factor 8
Rho guanine nucleotide exchange factor GEF 8
Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase. May be involved in activation of the SAPK/JNK pathway Stimulates genotoxic stress-induced RHOB activity in breast cancer cells leading to their cell death.