Recombinant Human Neurogranin protein (ab181939)
Key features and details
- Expression system: Escherichia coli
- Purity: > 90% SDS-PAGE
- Tags: His tag N-Terminus
- Suitable for: MS, SDS-PAGE
Description
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Product name
Recombinant Human Neurogranin protein
See all Neurogranin proteins and peptides -
Purity
> 90 % SDS-PAGE.
ab181939 was purified using conventional chromatography. -
Expression system
Escherichia coli -
Accession
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Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
MGSSHHHHHHSSGLVPRGSHMGSMDCCTENACSKPDDDILDIPLDDPGAN AAAAKIQASFRGHMARKKIKSGERGRKGPGPGGPGGAGVARGGAGGGPSG D -
Predicted molecular weight
10 kDa including tags -
Amino acids
1 to 78 -
Tags
His tag N-Terminus -
Additional sequence information
NP_001119653
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Associated products
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Related Products
Specifications
Our Abpromise guarantee covers the use of ab181939 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
Mass Spectrometry
SDS-PAGE
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Mass spectrometry
MALDI-TOF -
Form
Liquid -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 7.00
Constituents: 30% Glycerol (glycerin, glycerine), 0.002% PMSF, 0.32% Tris HCl, 0.03% EDTA
General Info
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Alternative names
- Protein kinase C substrate RC3
- Calmodulin binding protein
- Hng
see all -
Function
Acts as a "third messenger" substrate of protein kinase C-mediated molecular cascades during synaptic development and remodeling. Binds to calmodulin in the absence of calcium. -
Tissue specificity
In the cerebral cortex, found in the cell bodies of neurons in layers II-VI, and in apical and basal dendrites of pyramidal neurons. Is not found in the dendrites in patients with Alzheimer disease. -
Sequence similarities
Belongs to the neurogranin family.
Contains 1 collagen-like domain.
Contains 1 IQ domain. - Information by UniProt
Images
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
References (0)
ab181939 has not yet been referenced specifically in any publications.