Recombinant Human Neurogranin protein (ab181939)
- Datasheet
- References
- Protocols
Description
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Product name
Recombinant Human Neurogranin protein
See all Neurogranin proteins and peptides -
Purity
> 90 % SDS-PAGE.
ab181939 was purified using conventional chromatography. -
Expression system
Escherichia coli -
Accession
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Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
MGSSHHHHHHSSGLVPRGSHMGSMDCCTENACSKPDDDILDIPLDDPGAN AAAAKIQASFRGHMARKKIKSGERGRKGPGPGGPGGAGVARGGAGGGPSG D -
Predicted molecular weight
10 kDa including tags -
Amino acids
1 to 78 -
Tags
His tag N-Terminus -
Additional sequence information
NP_001119653
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Associated products
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Related Products
Specifications
Our Abpromise guarantee covers the use of ab181939 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
Mass Spectrometry
SDS-PAGE
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Mass spectrometry
MALDI-TOF -
Form
Liquid -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 7.00
Constituents: 30% Glycerol, 0.002% PMSF, 0.32% Tris HCl, 0.03% EDTA
General Info
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Alternative names
- Protein kinase C substrate RC3
- Calmodulin binding protein
- Hng
see all -
Function
Acts as a "third messenger" substrate of protein kinase C-mediated molecular cascades during synaptic development and remodeling. Binds to calmodulin in the absence of calcium. -
Tissue specificity
In the cerebral cortex, found in the cell bodies of neurons in layers II-VI, and in apical and basal dendrites of pyramidal neurons. Is not found in the dendrites in patients with Alzheimer disease. -
Sequence similarities
Belongs to the neurogranin family.
Contains 1 collagen-like domain.
Contains 1 IQ domain. - Information by UniProt
Images
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SDS-PAGE - Recombinant Human Neurogranin protein (ab181939)15% SDS-PAGE analysis of 3 µg ab181939.
Datasheets and documents
References
ab181939 has not yet been referenced specifically in any publications.
