Description

  • Product name

    Recombinant Human NFATC2IP protein
  • Expression system

    Wheat germ
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MSEPLQSVVDHMATHLGVSPSRILLLFGETELSPTATPRTLKLGVADIID CVVLTSSPEATETSQQLQLRVQGKEKHQTLEVSLSRDSPLKTLMSHYEEA MGLSGRKLSFFFDGTKLSGRELPADLGMESGDLIEVWG
    • Amino acids

      1 to 138
    • Tags

      GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab164685 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Western blot

  • Form

    Liquid
  • Additional notes

    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • 45 kDa NF-AT-interacting protein
    • 45 kDa NFAT-interacting protein
    • cytoplasmic 2-interacting protein
    • ESC2
    • NF2IP_HUMAN
    • NFAT-interacting protein, 45-KD
    • NFATC2-interacting protein
    • Nfatc2ip
    • NIP45
    • Nuclear factor of activated T-cells
    • Nuclear factor of activated T-cells, cytoplasmic 2-interacting protein
    • nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein
    • RAD60
    see all
  • Function

    Plays a role in the inducible expression of cytokine genes in T-cells, especially by increasing NFAT-driven IL-4 production.
  • Sequence similarities

    Contains 1 ubiquitin-like domain.
  • Post-translational
    modifications

    Methylation at the N-terminus by PRMT1 modulates interaction with the NFAT complex and results in augmented cytokine production.
  • Cellular localization

    Nucleus. Cytoplasm. TRAF1 is associated with a fraction of NFATC2IP in the cytoplasm and prevents its translocation to the nucleus.
  • Information by UniProt

Images

  • ab164685 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab164685 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab164685.
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