Recombinant Human NKF3 kinase family member/PEAK1 protein (ab164128)

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Description

  • Product name

    Recombinant Human NKF3 kinase family member/PEAK1 protein

  • Expression system

    Wheat germ

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      TPPPLPKKMIIRANTEPISKDLQKSMESSLCVMANPTYDIDPNWDASSAG SSISYELKGLDIESYDSLERPLRKERPVPSAANSISSLTTLSIKDRFSNS

    • Amino acids

      1151 to 1250

    • Tags

      GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab164128 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Western blot

  • Form

    Liquid

  • Additional notes

    This product was previously labelled as NKF3 kinase family member.

     

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • FLJ21140
    • FLJ34483
    • KIAA2002
    • NKF3 kinase family member
    • PEAK1
    • PEAK1_HUMAN
    • pseudopodium enriched atypical kinase
    • Pseudopodium-enriched atypical kinase 1
    • SGK269
    • Sugen kinase 269
    • Tyrosine-protein kinase SgK269
    see all

  • Function

    Tyrosine kinase that may play a role in cell spreading and migration on fibronectin. May directly or indirectly affect phosphorylation levels of cytoskeleton-associated proteins MAPK1/ERK and PXN.

  • Sequence similarities

    Belongs to the protein kinase superfamily.
    Contains 1 protein kinase domain.

  • Post-translational
    modifications

    Phosphorylated on tyrosine in a CSK-dependent manner in response to adhesion to fibronectin and to EGF stimulation. Autophosphorylated in vitro.

  • Cellular localization

    Cytoplasm > cytoskeleton. Cell junction > focal adhesion. Colocalizes with F-actin in serum-rich medium. Actin colocalization is reduced during serum starvation.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human NKF3 kinase family member/PEAK1 protein (ab164128)
    SDS-PAGE - Recombinant Human NKF3 kinase family member/PEAK1 protein (ab164128)
    ab164128 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab164128 has not yet been referenced specifically in any publications.

Publishing research using ab164128? Please let us know so that we can cite the reference in this datasheet.

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