Overview

  • Product name

    Recombinant Human NLRC4 protein
  • Protein length

    Protein fragment

Description

  • Nature

    Recombinant
  • Source

    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species

      Human
    • Molecular weight

      52 kDa including tags
    • Amino acids

      764 to 1019
    • Tags

      His-DHFR tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab127060 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Lyophilised
  • Additional notes

     This product was previously labelled as CARD12

     

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20ºC.

    Constituents: 0.32% Tris HCl, 0.58% Sodium chloride

  • Reconstitution
    Reconstitute with water to desired concentration.

General Info

  • Alternative names

    • and NACHT-containing protein
    • CARD
    • CARD 12
    • CARD LRR and NACHT containing protein
    • CARD LRR and NACHT containing protein 1
    • CARD12
    • Caspase recruitment domain containing protein 12
    • Caspase recruitment domain family member 12
    • Caspase recruitment domain-containing protein 12
    • CLAN
    • CLAN 1
    • CLAN A
    • CLAN B
    • CLAN C
    • CLAN D
    • Clan protein
    • CLAN1
    • CLANA
    • CLANB
    • CLANC
    • CLAND
    • CLR 2.1
    • CLR2.1
    • ICE protease activating factor
    • Ice protease-activating factor
    • Ipaf
    • LRR
    • NLR family CARD domain containing 4
    • NLR family CARD domain-containing protein 4
    • NLRC 4
    • NLRC4
    • NLRC4_HUMAN
    • NOD like receptor C4
    • Nucleotide binding oligomerization domain leucine rich repeat and CARD domain containing 4
    • UNQ6189/PRO20215
    see all
  • Function

    Plays a role in the promotion of apoptosis.
  • Tissue specificity

    Isoform 2 is expressed ubiquitously, although highly expressed in lung and spleen. Isoform 1 is highly expressed in lung, followed by leukocytes especially monocytes, lymph node, colon, brain, prostate, placenta, spleen, bone marrow and fetal liver. Isoform 4 is only detected in brain.
  • Sequence similarities

    Contains 1 CARD domain.
    Contains 14 LRR (leucine-rich) repeats.
    Contains 1 NACHT domain.
  • Cellular localization

    Cytoplasm. Cytoplasmic filaments.
  • Information by UniProt

References

ab127060 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab127060.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up