Recombinant human NME2 protein (ab211313)

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Description

  • Product name

    Recombinant human NME2 protein
    See all NME2 proteins and peptides

  • Biological activity

    Specific activity is >1,800 units/mg, and is defined as the amount of enzyme that convert 1.0 umole each of ATP and TDP to ADP and TTP per minute at pH 7.5 at 25°C in a couple system with PK/LDH.

  • Purity

    > 90 % SDS-PAGE.
    ab211313 was purified using conventional chromatography techniques.

  • Expression system

    Escherichia coli

  • Accession

    P22392

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      MANLERTFIA IKPDGVQRGL VGEIIKRFEQ KGFRLVAMKF LRASEEHLKQ HYIDLKDRPF FPGLVKYMNS GPVVAMVWEG LNVVKTGRVM LGETNPADSK PGTIRGDFCI QVGRNIIHGS DSVKSAEKEI SLWFKPEELV DYKSCAHDWV YE

    • Predicted molecular weight

      17 kDa

    • Amino acids

      1 to 152

    • Additional sequence information

      NP_001018149.

Specifications

Our Abpromise guarantee covers the use of ab211313 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Functional Studies

    Mass Spectrometry

    SDS-PAGE

  • Mass spectrometry

    MALDI-TOF

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8
    Constituents: 0.32% Tris HCl, 0.02% DTT, 10% Glycerol

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names

    • C myc purine binding transcription factor PUF
    • C myc transcription factor
    • C-myc purine-binding transcription factor PUF
    • epididymis secretory sperm binding protein Li 155an
    • HEL-S-155an
    • Histidine protein kinase NDKB
    • MGC111212
    • MGC2212
    • NDK B
    • NDKB
    • NDKB_HUMAN
    • NDP kinase B
    • NDPK B
    • NDPKB
    • NM23 H2
    • nm23-H2
    • NM23B
    • NME/NM23 nucleoside diphosphate kinase 2
    • nme2
    • Non metastatic cells 2, protein (NM23B) expressed in
    • non-metastatic cells 2, protein (NM23) expressed in
    • Nucleoside diphosphate kinase B
    • Nucleotide diphosphate kinase B
    • PUF
    see all

  • Function

    Major role in the synthesis of nucleoside triphosphates other than ATP. Negatively regulates Rho activity by interacting with AKAP13/LBC. Acts as a transcriptional activator of the MYC gene; binds DNA non-specifically (PubMed:8392752). Exhibits histidine protein kinase activity.

  • Tissue specificity

    Ubiquitously expressed.

  • Sequence similarities

    Belongs to the NDK family.

  • Cellular localization

    Cytoplasm. Nucleus. Isoform 2 is mainly cytoplasmic and isoform 1 and isoform 2 are excluded from the nucleolus.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant human NME2 protein (ab211313)
    SDS-PAGE - Recombinant human NME2 protein (ab211313)

    15% SDS-PAGE analysis of ab211313 (3 μg).

References

ab211313 has not yet been referenced specifically in any publications.

Publishing research using ab211313? Please let us know so that we can cite the reference in this datasheet.

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