Description

  • Product name

    Recombinant human NME2 protein
    See all NME2 proteins and peptides
  • Biological activity

    Specific activity is >1,800 units/mg, and is defined as the amount of enzyme that convert 1.0 umole each of ATP and TDP to ADP and TTP per minute at pH 7.5 at 25°C in a couple system with PK/LDH.

  • Purity

    > 90 % SDS-PAGE.
    ab211313 was purified using conventional chromatography techniques.
  • Expression system

    Escherichia coli
  • Accession

  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MANLERTFIA IKPDGVQRGL VGEIIKRFEQ KGFRLVAMKF LRASEEHLKQ HYIDLKDRPF FPGLVKYMNS GPVVAMVWEG LNVVKTGRVM LGETNPADSK PGTIRGDFCI QVGRNIIHGS DSVKSAEKEI SLWFKPEELV DYKSCAHDWV YE
    • Predicted molecular weight

      17 kDa
    • Amino acids

      1 to 152
    • Additional sequence information

      NP_001018149.

Specifications

Our Abpromise guarantee covers the use of ab211313 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Functional Studies

    Mass Spectrometry

    SDS-PAGE

  • Mass spectrometry

    MALDI-TOF
  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8
    Constituents: 0.32% Tris HCl, 0.02% DTT, 10% Glycerol

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names

    • C myc purine binding transcription factor PUF
    • C myc transcription factor
    • C-myc purine-binding transcription factor PUF
    • epididymis secretory sperm binding protein Li 155an
    • HEL-S-155an
    • Histidine protein kinase NDKB
    • MGC111212
    • MGC2212
    • NDK B
    • NDKB
    • NDKB_HUMAN
    • NDP kinase B
    • NDPK B
    • NDPKB
    • NM23 H2
    • nm23-H2
    • NM23B
    • NME/NM23 nucleoside diphosphate kinase 2
    • nme2
    • Non metastatic cells 2, protein (NM23B) expressed in
    • non-metastatic cells 2, protein (NM23) expressed in
    • Nucleoside diphosphate kinase B
    • Nucleotide diphosphate kinase B
    • PUF
    see all
  • Function

    Major role in the synthesis of nucleoside triphosphates other than ATP. Negatively regulates Rho activity by interacting with AKAP13/LBC. Acts as a transcriptional activator of the MYC gene; binds DNA non-specifically (PubMed:8392752). Exhibits histidine protein kinase activity.
  • Tissue specificity

    Ubiquitously expressed.
  • Sequence similarities

    Belongs to the NDK family.
  • Cellular localization

    Cytoplasm. Nucleus. Isoform 2 is mainly cytoplasmic and isoform 1 and isoform 2 are excluded from the nucleolus.
  • Information by UniProt

Images

  • 15% SDS-PAGE analysis of ab211313 (3 μg).

References

ab211313 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab211313.
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