Description

  • Product name

    Recombinant Human NPL protein
  • Purity

    > 95 % SDS-PAGE.
    ab106873 is purified using conventional chromatography techniques.
  • Expression system

    Escherichia coli
  • Accession

  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MGSSHHHHHHSSGLVPRGSHMAFPKKKLQGLVAATITPMTENGEINFSVI GQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQVAEEWVTKGKDKLDQ VIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILINFLKE VAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLL DFGQCVDQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQM LEAFEQKDFSLALNYQFCIQRFINFVVKLGFGVSQTKAIMTLVSGIPMGP PRLPLQKASREFTDSAEAKLKSLDFLSFTDLKDGNLEAGS
    • Predicted molecular weight

      37 kDa including tags
    • Amino acids

      1 to 320
    • Tags

      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab106873 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry

    MALDI-TOF
  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.0154% DTT, 0.316% Tris HCl, 20% Glycerol, 0.58% Sodium chloride

General Info

  • Alternative names

    • 0610033B02Rik
    • C112
    • C1orf13
    • Dihydrodipicolinate synthase
    • Dihydrodipicolinate synthetase homolog 1
    • MGC149582
    • MGC61869
    • N-acetylneuraminate lyase
    • N-acetylneuraminate pyruvate-lyase
    • N-acetylneuraminic acid aldolase
    • NAL
    • NALase
    • NPL
    • NPL_HUMAN
    • NPL1
    • RP11-249O6.1
    • Sialate lyase
    • Sialate-pyruvate lyase
    • Sialic acid aldolase
    • Sialic acid lyase
    see all
  • Function

    Catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate. It prevents sialic acids from being recycled and returning to the cell surface.
  • Tissue specificity

    Isoform 2 is expressed in placenta, liver, kidney, pancreas, spleen, thymus, ovary, small intestine and peripheral blood leukocyte.
  • Pathway

    Amino-sugar metabolism; N-acetylneuraminate degradation; D-fructose 6-phosphate from N-acetylneuraminate: step 1/5.
  • Sequence similarities

    Belongs to the DHDPS family. NanA subfamily.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt

Images

  • 15% SDS-PAGE analysis of 3µg ab106873.

References

ab106873 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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