Recombinant Human NPR-A protein (ab201407)

Submit a review Submit a question
SDS-PAGE - Recombinant Human NPR-A protein (ab201407)

    Key features and details

    • Expression system: Baculovirus infected Sf9 cells
    • Purity: > 75% SDS-PAGE
    • Tags: GST tag N-Terminus
    • Suitable for: SDS-PAGE

    Description

    • Product name

      Recombinant Human NPR-A protein
      See all NPR-A proteins and peptides

    • Purity

      > 75 % SDS-PAGE.

    • Expression system

      Baculovirus infected Sf9 cells

    • Accession

      P16066

    • Protein length

      Protein fragment

    • Animal free

      No

    • Nature

      Recombinant

      • Species

        Human

      • Sequence

        RKMQLE KELASELWRV RWEDVEPSSL ERHLRSAGSR LTLSGRGSNY GSLLTTEGQF QVFAKTAYYK GNLVAVKRVN RKRIELTRKV LFELKHMRDV QNEHLTRFVG ACTDPPNICI LTEYCPRGSL QDILENESIT LDWMFRYSLT NDIVKGMLFL HNGAICSHGN LKSSNCVVDG RFVLKITDYG LESFRDLDPE QGHTVYAKKL WTAPELLRMA SPPVRGSQAG DVYSFGIILQ EIALRSGVFH VEGLDLSPKE IIERVTRGEQ PPFRPSLALQ SHLEELGLLM QRCWAEDPQE RPPFQQIRLT LRKFNRENSS NILDNLLSRM EQYANNLEEL VEERTQAYLE EKRKAEALLY QILPHSVAEQ LKRGETVQAE AFDSVTIYFS DIVGFTALSA ESTPMQVVTL LNDLYTCFDA VIDNFDVYKV ETIGDAYMVV SGLPVRNGRL HACEVARMAL ALLDAVRSFR IRHRPQEQLR LRIGIHTGPV CAGVVGLKMP RYCLFGDTVN TASRMESNGE ALKIHLSSET KAVLEEFGGF ELELRGDVEM KGKGKVRTYW LLGERGSSTR G

      • Predicted molecular weight

        88 kDa including tags

      • Amino acids

        495 to 1061

      • Tags

        GST tag N-Terminus

      • Additional sequence information

        (BC063304)

    Specifications

    Our Abpromise guarantee covers the use of ab201407 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

    • Form

      Liquid

    • Additional notes

      Previously labelled as Natriuretic Peptide Receptor A. 

    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped on Dry Ice. Store at -80°C. Avoid freeze / thaw cycle.

      pH: 7.50
      Constituents: 0.79% Tris HCl, 0.29% Sodium chloride, 0.31% Glutathione, 0.003% EDTA, 0.004% DTT, 0.002% PMSF, 25% Glycerol (glycerin, glycerine)

    General Info

    • Alternative names

      • ANP-A
      • ANPa
      • ANPR-A
      • ANPRA
      • ANPRA_HUMAN
      • Atrial natriuretic peptide A type receptor
      • Atrial natriuretic peptide receptor 1
      • Atrial natriuretic peptide receptor A
      • Atrial natriuretic peptide receptor type A
      • Atrionatriuretic peptide receptor A
      • GC A
      • GC-A
      • Guanylate cyclase
      • Guanylate cyclase A
      • GUC2A
      • GUCY2A
      • Natriuretic peptide A type receptor
      • Natriuretic Peptide Receptor A
      • Natriuretic peptide receptor A/guanylate cyclase A
      • NPR-A
      • NPR1
      • NPRA
      see all

    • Function

      Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Has guanylate cyclase activity upon binding of the ligand.

    • Sequence similarities

      Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
      Contains 1 guanylate cyclase domain.
      Contains 1 protein kinase domain.

    • Post-translational
      modifications

      Phosphorylation of the protein kinase-like domain is required for full activation by ANP.

    • Cellular localization

      Membrane.
    • Information by UniProt

    Images

    • SDS-PAGE - Recombinant Human NPR-A protein (ab201407)
      SDS-PAGE - Recombinant Human NPR-A protein (ab201407)

      SDS PAGE analysis of ab201407

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab201407? Please let us know so that we can cite the reference in this datasheet.

    ab201407 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    Show All Reviews Q&A
    Submit a review Submit a question

    There are currently no Customer reviews or Questions for ab201407.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com