Recombinant Human NPR-A protein (Tagged) (ab235810)
Key features and details
- Expression system: Escherichia coli
- Purity: > 90% SDS-PAGE
- Tags: His tag N-Terminus
- Suitable for: MS, SDS-PAGE
Description
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Product name
Recombinant Human NPR-A protein (Tagged)
See all NPR-A proteins and peptides -
Purity
> 90 % SDS-PAGE. -
Expression system
Escherichia coli -
Accession
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Protein length
Protein fragment -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
GNLTVAVVLPLANTSYPWSWARVGPAVELALAQVKARPDLLPGWTVRTVL GSSENALGVCSDTAAPLAAVDLKWEHNPAVFLGPGCVYAAAPVGRFTAHW RVPLLTAGAPALGFGVKDEYALTTRAGPSYAKLGDFVAALHRRLGWERQA LMLYAYRPGDEEHCFFLVEGLFMRVRDRLNITVDHLEFAEDDLSHYTRLL RTMPRKGRVIYICSSPDAFRTLMLLALEAGLCGEDYVFFHLDIFGQSLQG GQGPAPRRPWERGDGQDVSARQAFQAAKIITYKDPDNPEYLEFLKQLKHL AYEQFNFTMEDGLVNTIPASFHDGLLLYIQAVTETLAHGGTVTDGENITQ RMWNRSFQGVTGYLKIDSSGDRETDFSLWDMDPENGAFRVVLNYNGTSQE LVAVSGRKLNWPLGYPPPDIPKCGFDNEDPACNQDHLSTLE -
Predicted molecular weight
65 kDa including tags -
Amino acids
33 to 473 -
Tags
His tag N-Terminus -
Additional sequence information
N-terminal 6xHis-SUMO-tagged. Extracellular domain.
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Associated products
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Related Products
Specifications
Our Abpromise guarantee covers the use of ab235810 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
Mass Spectrometry
SDS-PAGE
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Form
Liquid -
Additional notes
Previously labelled as Natriuretic Peptide Receptor A.
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Constituents: Tris buffer, 50% Glycerol (glycerin, glycerine)
General Info
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Alternative names
- ANP-A
- ANPa
- ANPR-A
see all -
Function
Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Has guanylate cyclase activity upon binding of the ligand. -
Sequence similarities
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
Contains 1 guanylate cyclase domain.
Contains 1 protein kinase domain. -
Post-translational
modificationsPhosphorylation of the protein kinase-like domain is required for full activation by ANP. -
Cellular localization
Membrane. - Information by UniProt
Images
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SDS-PAGE - Recombinant Human NPR-A protein (Tagged) (ab235810)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel analysis of ab235810.
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Mass Spectrometry - Recombinant Human NPR-A protein (Tagged) (ab235810)Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of ab235810 could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) NPR-A.
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Mass Spectrometry - Recombinant Human NPR-A protein (Tagged) (ab235810)Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of ab235810 could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) NPR-A
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
References (0)
ab235810 has not yet been referenced specifically in any publications.
