Recombinant Human NSL1 protein (denatured) (ab167875)

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Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
      Q96IY1
    • Species
      Human
    • Sequence
      MGSSHHHHHH SSGLVPRGSH MGSMAGSPEL VVLDPPWDKE LAAGTESQAL VSATPREDFR VRCTSKRAVT EMLQLCGRFV QKLGDALPEE IREPALRDAQ WTFESAVQEN ISINGQAWQE ASDNCFMDSD IKVLEDQFDE IIVDIATKRK QYPRKILECV IKTIKAKQEI LKQYHPVVHP LDLKYDPDPA PHMENLKCRG ETVAKEISEA MKSLPALIEQ GEGFSQVLRM QPVIHLQRIH QEVFSSCHRK PDAKPENFIT QIETTPTETA SRKTSDMVLK RKQTKDCPQR KWYPLRPKKI NLDT
    • Molecular weight
      35 kDa including tags
    • Amino acids
      1 to 281
    • Tags
      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab167875 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity
    < 85 % SDS-PAGE.

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris-HCl buffer, 2.4% Urea, 10% Glycerol

General Info

  • Alternative names
    • 4833432M17Rik
    • AI451597
    • C1orf48
    • DC31
    • DC8
    • DKFZp566O1646
    • Gm105
    • Gm984
    • Kinetochore associated protein NSL1 homolog
    • Kinetochore-associated protein NSL1 homolog
    • MIS14
    • NSL1
    • NSL1, MIND kinetochore complex component, homolog (S. cerevisiae)
    • NSL1_HUMAN
    see all
  • Function
    Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localization
    Nucleus. Chromosome > centromere > kinetochore. Associated with the kinetochore.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human NSL1 protein (denatured) (ab167875)
    SDS-PAGE - Recombinant Human NSL1 protein (denatured) (ab167875)
    15% SDS-PAGE analysis of ab167875 (3µg)

References

ab167875 has not yet been referenced specifically in any publications.

Publishing research using ab167875? Please let us know so that we can cite the reference in this datasheet.

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