Description

  • Product name

    Recombinant Human NTPDase 8 protein
  • Expression system

    Escherichia coli
  • Accession

  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Predicted molecular weight

      17 kDa
    • Amino acids

      305 to 458
    • Tags

      His-DHFR tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab127374 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Lyophilised
  • Additional notes

    Previously labelled as ENTPD8. 

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20ºC.

    Constituents: 0.32% Tris HCl, 0.58% Sodium chloride

  • Reconstitution
    Reconstitute with water to desired concentration.

General Info

  • Alternative names

    • E NTPDase 8
    • EC 3.6.1.5
    • ecto-ATP-diphosphohydrolase
    • Ectonucleoside triphosphate diphosphohydrolase 8
    • ENTPD8
    • GLSR2492
    • liver ecto ATP diphosphohydrolase
    • NTPDase 8
    • nucleoside triphosphate diphosphohydrolase-8
    • UNQ2492
    see all
  • Relevance

    NTPDase 8 is a canalicular ectonucleoside NTPDase responsible for the main hepatic NTPDase activity. Ectonucleoside NTPDases catalyze the hydrolysis of gamma- and beta-phosphate residues of nucleotides, playing a central role in concentration of extracellular nucleotides. Has activity toward ATP, ADP, UTP and UDP, but not toward AMP. There are two different isoforms.
  • Cellular localization

    Cell membrane; Multi-pass membrane protein

References

ab127374 has not yet been referenced specifically in any publications.

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