Description

  • Product name

    Recombinant Human NUBP2 protein
  • Purity

    > 90 % SDS-PAGE.
    ab187482 was purified using conventional chromatography.
  • Expression system

    Escherichia coli
  • Accession

  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MGSSHHHHHH SSGLVPRGSH MGSMEAAAEP GNLAGVRHII LVLSGKGGVG KSTISTELAL ALRHAGKKVG ILDVDLCGPS IPRMLGAQGR AVHQCDRGWA PVFLDREQSI SLMSVGFLLE KPDEAVVWRG PKKNALIKQF VSDVAWGELD YLVVDTPPGT SDEHMATIEA LRPYQPLGAL VVTTPQAVSV GDVRRELTFC RKTGLRVMGI VENMSGFTCP HCTECTSVFS RGGGEELAQL AGVPFLGSVP LDPALMRTLE EGHDFIQEFP GSPAFAALTS IAQKILDATP ACLP
    • Predicted molecular weight

      31 kDa including tags
    • Amino acids

      1 to 271
    • Tags

      His tag N-Terminus
    • Additional sequence information

      NCBI Accession No.: NP_036357

Specifications

Our Abpromise guarantee covers the use of ab187482 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry

    MALDI-TOF
  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 7.40
    Constituents: 0.02% DTT, 50% Glycerol, 49% PBS

General Info

  • Alternative names

    • C447E6.1 (nucleotide binding protein 1 (E.coli MinD like) )
    • CFD1
    • Cytosolic Fe-S cluster assembly factor NUBP2
    • D17Wsu11e
    • Homolog of yeast cytosolic FeS cluster deficient 1
    • NBP 2
    • NUBP1
    • Nubp2
    • NUBP2_HUMAN
    • Nucleotide binding protein 2
    • Nucleotide binding protein 2 (E.coli MinD like)
    • Nucleotide binding protein 2 (MinD homolog, E. coli)
    • Nucleotide-binding protein 2
    see all
  • Function

    Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
  • Tissue specificity

    Widely expressed with highest expression in skeletal muscle.
  • Sequence similarities

    Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.
  • Developmental stage

    Expressed in fetal brain, lung, liver and kidney.
  • Cellular localization

    Nucleus. Cytoplasm > cytoskeleton > microtubule organizing center > centrosome. Enriched at the centrosomes during mitosis.
  • Information by UniProt

Images

  • 15% SDS-PAGE analysis of ab187482 (3 µg)

References

ab187482 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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