Recombinant Human OASL protein (ab160131)
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Description
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Product name
Recombinant Human OASL protein -
Expression system
Wheat germ -
Protein length
Protein fragment -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
MALMQELYSTPASRLDSFVAQWLQPHREWKEEVLDAVRTVEEFLRQEHFQ GKRGLDQDVRVLKVVKVGSFGNGTVLRSTREVELVAFLSCFHSFQEAAKH -
Amino acids
1 to 100 -
Tags
GST tag N-Terminus
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Specifications
Our Abpromise guarantee covers the use of ab160131 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
Western blot
ELISA
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Form
Liquid -
Additional notes
Protein concentration is above or equal to 0.05 mg/ml. -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
General Info
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Alternative names
- 2' 5' oligoadenylate synthetase like
- 2''-5''-OAS-related protein
- 2''-5''-OAS-RP
see all -
Function
Does not have 2'-5'-OAS activity, but can bind double-stranded RNA. Displays antiviral activity against encephalomyocarditis virus (EMCV) and hepatitis C virus (HCV) via an alternative antiviral pathway independent of RNase L. -
Tissue specificity
Expressed in most tissues, with the highest levels in primary blood Leukocytes and other hematopoietic system tissues, colon, stomach and to some extent in testis. -
Sequence similarities
Belongs to the 2-5A synthase family.
Contains 2 ubiquitin-like domains. -
Domain
The ubiquitin-like domains are essential for its antiviral activity. -
Cellular localization
Cytoplasm and Nucleus > nucleolus. Cytoplasm. - Information by UniProt
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Datasheets and documents
References
ab160131 has not yet been referenced specifically in any publications.