Overview

  • Product name
    Recombinant Human OASL protein
  • Protein length
    Protein fragment

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      MALMQELYSTPASRLDSFVAQWLQPHREWKEEVLDAVRTVEEFLRQEHFQ GKRGLDQDVRVLKVVKVGSFGNGTVLRSTREVELVAFLSCFHSFQEAAKH
    • Amino acids
      1 to 100
    • Tags
      proprietary tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab160131 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • 2' 5' oligoadenylate synthetase like
    • 2''-5''-OAS-related protein
    • 2''-5''-OAS-RP
    • 2''-5''-oligoadenylate synthase-like protein
    • 2'-5' oligoadenylate synthetase-like 2
    • 2'-5'-oligoadenylate synthetase-like
    • 59 kDa 2' 5' oligoadenylate synthetase like protein
    • 59 kDa 2''-5''-oligoadenylate synthase-like protein
    • 59 kDa 2'-5'-oligoadenylate synthetase-like protein
    • M1204
    • Mmu-OASL
    • OASL
    • OASL_HUMAN
    • Oasl2
    • p59 OASL
    • p59OASL
    • THYROID HORMONE RECEPTOR INTERACTOR 14
    • Thyroid receptor interacting protein 14
    • Thyroid receptor-interacting protein 14
    • TR-interacting protein 14
    • TRIP-14
    • TRIP14
    see all
  • Function
    Does not have 2'-5'-OAS activity, but can bind double-stranded RNA. Displays antiviral activity against encephalomyocarditis virus (EMCV) and hepatitis C virus (HCV) via an alternative antiviral pathway independent of RNase L.
  • Tissue specificity
    Expressed in most tissues, with the highest levels in primary blood Leukocytes and other hematopoietic system tissues, colon, stomach and to some extent in testis.
  • Sequence similarities
    Belongs to the 2-5A synthase family.
    Contains 2 ubiquitin-like domains.
  • Domain
    The ubiquitin-like domains are essential for its antiviral activity.
  • Cellular localization
    Cytoplasm and Nucleus > nucleolus. Cytoplasm.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human OASL protein (ab160131)
    SDS-PAGE - Recombinant Human OASL protein (ab160131)
    ab160131 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab160131 has not yet been referenced specifically in any publications.

Publishing research using ab160131? Please let us know so that we can cite the reference in this datasheet.

Customer reviews and Q&As

Submit a review Submit a question

There are currently no Customer reviews or Questions for ab160131.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up